The ladies at the Renegade Writer give some thought to the importance (or not) of the signature line on an email. Me, I like just the facts, ma'am. I think it's nice when people find, say, an inspirational quote that they love, but it's practically invisible to me (unless I get confused and think it's some sort of postscript and I wonder, Wait, why is she talking to me about Anais Nin?. Having an unprofessional signature can also turn off an editor. But a funny one might make them laugh and like you. Read more about choosing one here.