Did you know that you can buy pretty much any New Yorker cartoon, printed on pretty much any piece of merchandise, at the Cartoon Bank? Well, now your life is that much closer to complete.

Head Cartoon Bank-er and New Yorker cartoon editor Bob Mankoff was the closer Friday night at Art Center’s Radical Craft conference, and although a “Family Guy” clip showed later accurately reflected our somewhat ambivalent relationship with the pretentious toons, Mankoff picked the cleverest of the crowd-pleasers and sent the audience off in stitches.

Mankoff studies cartoons at the University of Michigan, where watching eye movements and pupil widening can actually explain how “funny” a cartoon is. He also spoke about rejection–an essential piece of the cartoon craft. Let it be known that his own cartoons were rejected many (many) times before he sold one, then another, before he became the official Mayor of Toontown.