Flagship Pioneering Company
ML Scientist, Molecular Design Platform
Flagship Pioneering Company, Cambridge, Massachusetts, us, 02140
Overview
Get AI-powered advice on this job and more exclusive features. Company Description
FL117, a venture-back stealth AI x bio startup, is seeking a highly skilled
ML Scientist . Here you will build out the methods, models and data that guide the development of a next gen generative model for drug design. We are looking for those excited to work on ambitious projects in a fast-paced environment to push the frontier of AI-powered drug discovery.
Responsibilities
Collaborate with foundation modeling team on the development of next-gen models for drug design.
Implement the benchmarking protocols, baselines, splits and metrics necessary to guide development of a best-in-class molecular design software stack.
Conduct analysis of methods, models, and data to guide development of next-gen molecular design stack.
Identify, onboard and homogenize data from public and proprietary sources in a scalable and reproducible manner to train and benchmark a molecular generation platform.
Implementation of cheminformatics/bioinformatics pipelines to support the execution of molecular design and selection for synthesis and invitro screening.
Qualifications
MSc or PhD in Computer Science, AI/ML, Computational Biology/Chemistry, or a related field.
Prior experience with generative AI for chemistry and protein design
Strong Python skills and experience with PyTorch.
Prior experience curating/handling large public data
Preferred Experience
Contributed to open-source data projects in biology/chemistry. Please send your GitHub, if applicable.
Strong presence in the ML community through publications and conference proceedings. Please send a list of publications, if applicable.
Knowledge of biological data formats (FASTA, SDF, PDBx/mmCIF) and domain-specific ontologies/metadata standards
Experience with models like ESM, DiffDock, ProteinMPNN, OpenFold, etc.
Familiarity with ML software development and cloud services (Docker, AWS Batch, Step Functions, EKS, AWS ParallelCluster, etc.)
Experience with libraries like: rdkit, rosetta, prody, biopython, pymol, openmm, dagster, prefect, etc.
About Flagship Pioneering Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer . All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths
without fulfilling every qualification . If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background
and interest in Flagship .
Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
Location: Cambridge, MA
Salary: $175,000.00-$190,000.00
Seniority level Mid-Senior level
Employment type Full-time
Job function Research and Science Industries: Biotechnology Research and Research Services
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Get AI-powered advice on this job and more exclusive features. Company Description
FL117, a venture-back stealth AI x bio startup, is seeking a highly skilled
ML Scientist . Here you will build out the methods, models and data that guide the development of a next gen generative model for drug design. We are looking for those excited to work on ambitious projects in a fast-paced environment to push the frontier of AI-powered drug discovery.
Responsibilities
Collaborate with foundation modeling team on the development of next-gen models for drug design.
Implement the benchmarking protocols, baselines, splits and metrics necessary to guide development of a best-in-class molecular design software stack.
Conduct analysis of methods, models, and data to guide development of next-gen molecular design stack.
Identify, onboard and homogenize data from public and proprietary sources in a scalable and reproducible manner to train and benchmark a molecular generation platform.
Implementation of cheminformatics/bioinformatics pipelines to support the execution of molecular design and selection for synthesis and invitro screening.
Qualifications
MSc or PhD in Computer Science, AI/ML, Computational Biology/Chemistry, or a related field.
Prior experience with generative AI for chemistry and protein design
Strong Python skills and experience with PyTorch.
Prior experience curating/handling large public data
Preferred Experience
Contributed to open-source data projects in biology/chemistry. Please send your GitHub, if applicable.
Strong presence in the ML community through publications and conference proceedings. Please send a list of publications, if applicable.
Knowledge of biological data formats (FASTA, SDF, PDBx/mmCIF) and domain-specific ontologies/metadata standards
Experience with models like ESM, DiffDock, ProteinMPNN, OpenFold, etc.
Familiarity with ML software development and cloud services (Docker, AWS Batch, Step Functions, EKS, AWS ParallelCluster, etc.)
Experience with libraries like: rdkit, rosetta, prody, biopython, pymol, openmm, dagster, prefect, etc.
About Flagship Pioneering Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer . All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths
without fulfilling every qualification . If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background
and interest in Flagship .
Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
Location: Cambridge, MA
Salary: $175,000.00-$190,000.00
Seniority level Mid-Senior level
Employment type Full-time
Job function Research and Science Industries: Biotechnology Research and Research Services
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