Senior Research Associate - Next Generation Sequencing Library Prep Job at City

Overview Thank you for your interest. This posting is to recruit for on-going and future positions at the Beckman Research Institute of City of Hope. We are pursuing innovative research to fight cancer, diabetes, and other life-threatening illnesses and advance medicine through cutting-edge research. The Chintan Parekh Lab is seeking a Senior Research Associate to join the Pediatrics basic science research group. This role supports discovery programs by generating high-quality, reproducible data across genomics and proteomics platforms. You will be a hands-on laboratory specialist with expertise in Next-Generation Sequencing (NGS) library construction, with attention to detail and proactive protocol development. To learn more about Dr. Chintan Parekh, please visit here. Responsibilities Next-Generation Sequencing (NGS) Library Preparation (Main Focus): Independently perform end-to-end preparation of complex NGS libraries from diverse sample types (e.g., cells, tissues). Include established protocols for sequencing assays such as Transcriptomics (RNA-seq), Epigenetics (ATAC-seq and CUT&RUN), and Genetics (Exome Sequencing). Manage quality control steps (e.g., concentration, fragment analysis) and troubleshoot library workflows. Assay Development and Protocol Establishment: Establish, optimize, and document new laboratory protocols for cutting-edge sequencing assays. Evaluate and integrate reagents, kits, and technologies to improve efficiency and quality. Mass Spectrometry Sample Preparation: Prepare biological samples (e.g., protein lysates, fractionated samples) for Mass Spectrometry analysis. Qualifications Bachelors or Masters degree in Molecular Biology, Biochemistry, Genomics, or related field. 5+ years of related experience with a Bachelor's degree or 4+ years with a Master's degree. Direct, hands-on experience with NGS library preparation (e.g., RNA-seq, ATAC-seq). Excellent organizational skills with meticulous attention to detail and data integrity; ability to work independently and manage multiple projects in a fast-paced environment. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please CLICK HERE. #J-18808-Ljbffr