Head of Medical Affairs, North America

Overview

Join to apply for the Head of Medical Affairs, North America role at SpringWorks Therapeutics .

Location Classification – Hybrid: This role will be required to work onsite 2 days a week (Tuesday and Wednesday), or more depending on business needs.

About SpringWorks Therapeutics

SpringWorks Therapeutics, a healthcare company of Merck KGaA, Darmstadt, Germany, is a commercial-stage biopharmaceutical company dedicated to improving the lives of patients with rare tumors. We developed and are commercializing the first and only FDA and EC approved medicine for adults with desmoid tumors and the first and only FDA and EC approved medicine for both adults and children with neurofibromatosis type 1 associated plexiform neurofibromas (NF1-PN). At SpringWorks, we are committed to finding answers people with rare tumors need, and we value authenticity and collaboration to drive scientific progress.

Role Responsibilities

• Develop and ensure execution of clear medical affairs strategies for the U.S. and Canada, aligned with business and brand objectives.
• Lead teams to shape and adapt global strategies to address in-market needs for North America, ensuring customer needs are met.
• Provide Medical leadership across North America functional partners to drive in-market product strategy, disease positioning, and projects.
• Define and lead disease awareness initiatives, publication planning, advisory boards, and investigator-sponsored research (IITs).
• Drive post-marketing strategy and provide strategic input into late-stage clinical development.
• Represent the company in industry forums, patient advocacy groups, and scientific/clinical expert groups as needed.
• Facilitate cross-functional alignment with R&D, Commercial, and Global Medical Affairs to support pipeline and lifecycle success for SpringWorks and EMD Serono products.
• Lead and develop two high-performing medical affairs teams (SpringWorks NA and EMD Serono).
• Set strategic objectives, manage performance, coach talent, and ensure resource allocation and budget management.
• Ensure launch readiness and contribute to global and regional medical and publication plans.
• Establish relationships with key opinion leaders, healthcare professionals, and advocacy groups at national and international levels.
• Perform other duties as assigned.

Role Requirements

• Education: Doctor of Medicine (MD required)
• 15+ years of progressive experience in Medical Affairs or related functions, including global and regional roles
• 7+ years of people leadership, including 3+ years managing multiple functions or teams
• Track record of taking products from late-stage development through launch and lifecycle management
• Experience designing and executing medical affairs strategies, including post-approval clinical protocols
• Experience building and leading medical teams in dynamic environments
• Deep understanding of health economics, outcomes research, and health technology assessment
• Strong experience in building KOL networks nationally and internationally
• Ability to lead large teams and develop leaders of leaders
• Knowledge of SOPs and regulatory frameworks (FDA, PhRMA, OIG, etc.)
• Strong collaboration across external partnerships and cross-functional teams
• Knowledge of clinical research methodology and Good Clinical Practice (GCP) preferred
• Understanding of NA regulatory, medical, and economic environments
• Knowledge of real-world evidence generation, medical information, and commercialization support
• Strong business planning, data analysis, and budget management
• Executive-level understanding of the commercial, clinical, and regulatory aspects of the pharmaceutical industry
• Ability to translate complex scientific concepts into actionable strategies
• Willingness to travel domestically and internationally as required
• Model SpringWorks Leadership Principles to drive a collaborative function and growth mindset
• Demonstrate SpringWorks Values with empathy, humility, ownership, and accountability
• Strong interpersonal communication skills for remote hybrid work environment

SpringWorks Leadership Principles

• Change Steward
• Excellence Driver
• Growth Coach
• Community Builder

Compensation & Benefits

The expected salary range for this position is $450,000.00 – $500,000.00. A discretionary annual bonus may be available based on individual and company performance. We offer comprehensive benefits; additional information can be found in the Benefits section.

EEO Statement

SpringWorks maintains an EEO Policy providing equitable opportunities for employment and conditions of employment to all employees and applicants regardless of protected characteristics. SpringWorks’ Equal Employment Opportunity Policy ensures no barriers to hiring, promotion, or other employment opportunities. This policy applies to all aspects of employment and any violation will result in disciplinary action up to termination.

Privacy

Upon submission of this form I understand that SpringWorks Therapeutics is based in the United States and personal data submitted in the form will be transferred and accessed in the U.S.

Seniority level

Executive

Employment type

Full-time

Job function

Other