Executive Director, Clinical Operations
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity
This is a unique opportunity for the right individual who has innate and proven leadership and organizational skills, people mentoring and staff management professional, technical expertise in Clinical Operations Structure and Procedure in an industry setting, and experience in organizing clinical operations. As the Executive Director in Clinical Operations, you will be responsible for the operational design and structure of, and accountable for the implementation and continuation of, procedures, governance and expansions of processes and procedures to enable Revolution Medicines clinical trials.
Responsibilities
- Mentor and represent Clinical Operations Study Teams to vendor outsourcing leaders, synergizing strategy, building efficiencies, and collaborating with internal and external stakeholders.
- Shape clinical operations infrastructure to support high quality, efficient conduct and inspection‑ready clinical trials, including staff development tools, clinical process alignment, standardization, inspection‑ready clinical document management processes, and other systems.
- Identify gaps, align building of solutions, and drive evaluation, selection, deployment, and oversight of clinical operational resolutions.
- Build achievable standards that allow for consistent oversight and content management of clinical operations systems such as eTMF, Feasibility Work, LMS, Medical CRM, and CTMS.
- Oversee Clinical Operations resource planning, tracking and general strategy by partnering with RevMed management and appropriate fellow Clinical Operations and Functional Teams to support clinical study execution.
- Lead Clinical Operations teams and build partnerships with cross‑functional operations to ensure quality, timely and fiscally responsible deliverables across the RevMed portfolio.
- Cultivate collaborations with other functional groups to produce mutually beneficial, purposeful and operational objectives, deliverables, and creative solutions that meet current Global Industry ICH/GCP standards.
- Serve as a RevMed resource for Clinical Operations Systems, actively forecast and act to ensure Clinical Development plans/programs meet RevMed goals.
- May cross over into leading study functions and/or assume leadership responsibilities beyond mentorships.
- Lead and grow the Clinical Operations function and staff with a culture of respect, honesty, curiosity, empowerment and accountability for the achievement of their commitments and goals.
Required Skills, Experience and Education
- BS/MS Degree in a scientific discipline with a minimum of 15 years of clinical operations experience in the pharmaceutical or biotech industry, preferably majority in oncology drug development.
- Minimum of 10 years clinical operations systems project and line management experience.
- Extensive experience in leading and managing global phase 1‑3 clinical trials within designated timelines, resources, and budgets, and translating experiences into operational systems.
- Demonstrable record of strong leadership and teamwork.
- Extensive experience in selection of CROs/vendors and management of external resources.
- Working knowledge of data management, data review and analysis, drug safety, pharmacovigilance and other related functions related to clinical trial conduct.
- Strong working knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials.
- Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high‑energy environment.
- Excellent written and verbal communication skills.
- Ability to act as an excellent ambassador for Revolution Medicines in interactions with key opinion leaders, scientific advisors, corporate partners and, where necessary, investors.
- Demonstrated ability to multi‑task, prioritize options, anticipate challenges and execute goals as a member of an interdisciplinary team.
Preferred Skills
- Experience in working with cooperative group studies and investigator‑sponsored trials.
Compensation
Base pay salary range for this full‑time position for candidates working onsite at our headquarters in Redwood City, CA: $256,000 – $320,000 USD. The range is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market. Base pay is determined by role, level, location, skills, experience, market dynamics, and education.
Revolution Medicines offers competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Equal Opportunity Employer
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
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