Executive Director, Global Medical Affairs, GI
Summit Therapeutics Inc. is a biopharmaceutical oncology company focused on improving quality of life and addressing serious unmet medical needs. Our core values include integrity, passion for excellence, purposeful urgency, collaboration, and dedication to people. Summit’s global portfolio includes multiple Phase 3 clinical studies in oncology and gastrointestinal cancers.
Key GI clinical studies:
- HARMONi: Phase 3 study evaluating ivonescimab + chemotherapy vs placebo + chemotherapy in EGFR‑mutated NSCLC.
- HARMONi‑3: Phase 3 study evaluating ivonescimab + chemotherapy vs pembrolizumab + chemotherapy in first‑line metastatic NSCLC.
- HARMONi‑7: Phase 3 study evaluating ivonescimab monotherapy vs pembrolizumab monotherapy in first‑line metastatic NSCLC.
- HARMONi‑GI3: Phase 3 study evaluating ivonescimab + chemotherapy vs bevacizumab + chemotherapy in colorectal cancer.
Overview Of Role
The Executive Director of Medical Affairs, GI, is a key leader responsible for shaping and executing the medical affairs strategy in GI cancers. This role leads launch excellence, lifecycle management, and scientific engagement for lung‑related indications and collaborates cross‑functionally with Clinical Development, Regulatory Affairs, Commercial, and Market Access teams. Recent, hands‑on experience in GI cancers, either in clinical practice or within pharmaceutical companies, is essential.
Role And Responsibilities
- Strategic Leadership
- Develop and lead the US medical affairs strategy for GI cancers, ensuring alignment with global objectives.
- Oversee the design, execution, and reporting of medical activities supporting launch and lifecycle management.
- Foster a culture of high performance, collaboration, and scientific excellence across the medical affairs team.
- Team Leadership
- Lead a high‑performance matrixed team grounded in scientific rigor and integrity.
- Mentor, coach, and develop others, ensuring effective coverage and execution of medical initiatives.
- Scientific Engagement & Insight Generation
- Establish and maintain relationships with KOLs, HCPs, and other external stakeholders to support scientific exchange and gather actionable insights.
- Ensure effective communication of scientific data and information to external stakeholders, representing Summit at scientific conferences and other events.
- Oversee the development and execution of pre‑launch medical education programs, strategic publications, and data generation initiatives.
- Cross‑Functional Collaboration
- Collaborate with Clinical Development, Regulatory, Commercial, and other internal stakeholders to ensure strategic integration and alignment of medical activities.
- Compliance & Reporting
- Ensure all medical affairs activities comply with regulatory and company policies.
- Monitor and report on activities, performance metrics, and outcomes to senior leadership.
- Participate in the development and adherence to departmental SOPs and ensure all activities are legally compliant and conducted according to company standards.
- All other duties as assigned.
Experience, Education And Specialized Knowledge And Skills
- Education
- Advanced scientific degree (MD, PharmD, PhD) required.
- Experience
- Minimum of 12+ years progressive Medical Affairs or related experience, with at least 5+ years in a leadership role.
- Significant recent experience in GI cancers, either in clinical practice or within pharmaceutical/biotech companies, is required.
- Proven track record of supporting product launches, building and optimizing medical affairs teams, and managing through leaders.
- Experience in a fast‑paced, evolving environment preferred.
- Skills & Abilities
- Excellent leadership, communication, and stakeholder management skills.
- Strong analytical and strategic thinking abilities.
- Demonstrates resilience, composure, and effective decision‑making in a dynamic and challenging environment.
- Ability to thrive in a matrixed, cross‑functional environment.
- Demonstrated ability to motivate, develop, and retain high‑performing teams.
- Willingness to travel up to 40% as needed.
- Additional Requirements
- Proficient user of standard MS Office suite (Word, Excel), experience using electronic document management systems, and document review tools.
- Must be able to effectively multi‑task and manage time‑sensitive and highly confidential documents.
- Work in a fast‑paced, demanding, and collaborative environment.
Compensation: $231,000 - $289,000 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.
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