Ionis Pharmaceuticals, Inc.
Associate Director of Pathology
Ionis Pharmaceuticals, Inc., California, Missouri, United States, 65018
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.
At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.
With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.
We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!
ASSOCIATE DIRECTOR OF PATHOLOGY
Ionis is seeking a talented and highly motivated Pathologist within the Preclinical Development Department to provide strategic scientific leadership in the assessment of nonclinical safety of candidate medicines. The Preclinical Development Department includes highly collaborative scientists who provide a supportive environment that fosters growth and learning. Key responsibilities include:
Conduct histopathology review of internal and outsourced non-GLP and GLP research, pharmacology, and toxicology studies and provide interpretation that integrates all study data
Serve as nonclinical safety representative on cross-functional project teams based on interest
Contribute to the design of non-GLP and GLP nonclinical studies
Provide strategic input on the nonclinical toxicology and regulatory approach for IND-enabling packages and for clinical stage programs
Author nonclinical sections of regulatory documents (e.g. IB, IND, NDA, DSUR, etc) and represent Ionis in meetings with regulatory authorities
Assess mechanism(s) of toxicity to determine clinical relevance and impact
Communicate pathology and nonclinical safety findings, interpretation, and impact to teams and governance committees
Represent Ionis externally (e.g. at scientific meetings and/or through participation in industry consortia, working groups, and/or professional societies)
Publish findings in high impact peer-reviewed journal
REQUIREMENTS:
DVM (or equivalent)
PhD in pathology, toxicology, or related life sciences discipline
Board-certification in anatomic pathology (e.g. ACVP, ECVP)
At least 5 years of experience in toxicologic pathology of multiple species in the pharmaceutical or biotechnology field with a focus on IND-enabling packages and beyond
Experience with digital pathology and image analysis is a plus
Experience with regulatory submissions and interactions
Demonstrated strong decision-making and problem-solving skills
Team player with proven interpersonal and communication skills
Dedication to life-long learning and professional development
Please visit our website,
www.ionis.com
for more information about Ionis and to apply for this position; reference requisition #IONIS003712
Ionis Benefits
The pay scale for this position is $169K,000 to $237,000
NO PHONE CALLS PLEASE. PRINCIPALS ONLY. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Equal Opportunity Employer This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.
#J-18808-Ljbffr
At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.
With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.
We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!
ASSOCIATE DIRECTOR OF PATHOLOGY
Ionis is seeking a talented and highly motivated Pathologist within the Preclinical Development Department to provide strategic scientific leadership in the assessment of nonclinical safety of candidate medicines. The Preclinical Development Department includes highly collaborative scientists who provide a supportive environment that fosters growth and learning. Key responsibilities include:
Conduct histopathology review of internal and outsourced non-GLP and GLP research, pharmacology, and toxicology studies and provide interpretation that integrates all study data
Serve as nonclinical safety representative on cross-functional project teams based on interest
Contribute to the design of non-GLP and GLP nonclinical studies
Provide strategic input on the nonclinical toxicology and regulatory approach for IND-enabling packages and for clinical stage programs
Author nonclinical sections of regulatory documents (e.g. IB, IND, NDA, DSUR, etc) and represent Ionis in meetings with regulatory authorities
Assess mechanism(s) of toxicity to determine clinical relevance and impact
Communicate pathology and nonclinical safety findings, interpretation, and impact to teams and governance committees
Represent Ionis externally (e.g. at scientific meetings and/or through participation in industry consortia, working groups, and/or professional societies)
Publish findings in high impact peer-reviewed journal
REQUIREMENTS:
DVM (or equivalent)
PhD in pathology, toxicology, or related life sciences discipline
Board-certification in anatomic pathology (e.g. ACVP, ECVP)
At least 5 years of experience in toxicologic pathology of multiple species in the pharmaceutical or biotechnology field with a focus on IND-enabling packages and beyond
Experience with digital pathology and image analysis is a plus
Experience with regulatory submissions and interactions
Demonstrated strong decision-making and problem-solving skills
Team player with proven interpersonal and communication skills
Dedication to life-long learning and professional development
Please visit our website,
www.ionis.com
for more information about Ionis and to apply for this position; reference requisition #IONIS003712
Ionis Benefits
The pay scale for this position is $169K,000 to $237,000
NO PHONE CALLS PLEASE. PRINCIPALS ONLY. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Equal Opportunity Employer This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.
#J-18808-Ljbffr