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Vivid Resourcing

Director/Senior Director, CMC Regulatory Affairs

Vivid Resourcing, Boston, Massachusetts, us, 02298

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Director / Senior Director, Regulatory Affairs - CMC (Biologics | Phase 3 Asset | Advanced Modality) Boston area (hybrid, flexible travel)

A clinical-stage biotech developing an

advanced biologic therapy in Phase 3

is seeking a

Director/Senior Director of Regulatory Affairs, CMC

to lead regulatory strategy and execution for a pivotal autoimmune program approaching

BLA submission .

This is a

high-impact leadership role

suited to someone who combines deep regulatory CMC expertise with the agility to work cross-functionally in a lean biotech setting.

The Opportunity: You’ll be the

CMC regulatory lead

driving global submission strategy, from IND maintenance through BLA authoring and post-approval planning. You’ll partner closely with Manufacturing, Quality, and Supply Chain teams, shaping how the company engages with regulators across major markets.

Key Responsibilities:

Define and implement

global CMC regulatory strategy

for a late-stage biologic asset (Phase 3 → BLA).

Lead preparation, authoring, and review of

CMC sections

for IND, BLA, and global submissions.

Develop and execute the

BLA roadmap , determining content strategy, data presentation, and agency engagement plans.

Serve as the

primary CMC regulatory point of contact

with the FDA and other global agencies.

Partner cross-functionally with Manufacturing, Quality, and Technical Operations to ensure regulatory alignment throughout process development, validation, and lifecycle management.

Guide the organization on

advanced modality

expectations and best practices in biologics manufacturing.

Contribute to future

device strategy

(auto-injectors, prefilled syringes, infusion/IV delivery systems), helping define regulatory pathways for combination products.

Mentor and support junior regulatory professionals or cross-functional contributors, though this role is

not directly managerial

at present.

What We’re Looking For:

10+ years of

Regulatory Affairs experience , including direct

CMC responsibility

within biologics.

Proven track record supporting

late-stage submissions

(Phase 3 → BLA) and global regulatory filings.

Strong understanding of

manufacturing and analytical

CMC considerations for biologics.

Ability to build and execute

global regulatory strategies

across the U.S., EU, and other key regions.

Experience in

advanced modalities

or

drug–device combinations

highly preferred.

Collaborative communicator who can influence senior stakeholders while remaining detail-focused.

U.S.-based, with ability to travel to the Boston area a few times per quarter.

Why Join:

Opportunity to

own regulatory strategy

for a pivotal Phase 3 biologic asset.

Work within a

nimble, science-driven biotech

backed by strong scientific and operational teams.

Operate with

autonomy and visibility

across the full product lifecycle, from late clinical stage through potential licensure.

Reach out directly for a confidential discussion:

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