
Executive/Senior Director, Global Program Management
GlaxoSmithKline, Boston, Massachusetts, us, 02298
Site Name:
USA - Pennsylvania - Upper Providence, USA - Massachusetts - Boston Posted Date:
Feb 5 2026 Overview
Business Introduction: At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Position Summary: As the Senior Director of Program Management Oncology for a flagship oncology asset, you will be the driving force behind flawless execution—translating strategy into action and ensuring disciplined delivery of program milestones. You will shape critical decisions by influencing stakeholders through data-driven insights and external perspectives, while fostering a culture of accountability and agility. Your role demands operational rigor, proactive risk management, and the ability to challenge assumptions to accelerate progress without compromising quality or safety. Key Responsibilities
Acting as the Medicine Development Leader’s strategic partner and primary point of contact for the program’s Medicine Development Team (MDT), overseeing a complex, multi-tumor program—integrating clinical development, asset and evidence strategies into a unified vision. Lead all project management aspects of this high-visibility initiative, ensuring milestone delivery at pace while upholding quality and safety. Strategic Orchestration and Cross-Functional Leadership.
Integrate clinical, regulatory, CMC, and commercial strategies into a unified program plan; guide strategic discussions and encourage diverse viewpoints to reach actionable outcomes; leverage insights from external experts and benchmarks; maintain an overview of systems to identify dependencies and manage complexity. Demonstrate Critical Thinking
This requires questioning assumptions and exploring new approaches through insightful inquiries; simplify complex topics into actionable insights for senior leaders; work with Medicine Development Leaders to optimize asset strategy considering both business and patient needs. Agility Initiative, and Execution Excellence
Promote team adaptability to evolving data and priorities, lead scenario planning to minimize disruption while staying aligned with long-term objectives and clearly communicate changes to keep program goals in focus. Responsibilities
Take ownership of program execution, proactively resolve challenges, lead planning and risk management, track progress, identify opportunities for innovation and efficiency, and accelerate outcomes by streamlining decision-making and removing obstacles. Stakeholder Engagement and Facilitation Excellence
Engage with senior leaders, governance bodies, external partners, and subject matter experts; lead tailored meetings that enable decisive outcomes; cultivate trusted relationships and influence through credibility, data-driven insights, and composure; ensure program visibility through compelling storytelling and impactful dashboards. Governance, Communication and Executive Engagement
Facilitate governance interactions and translate complexity into clear, data-driven recommendations; summarize strategy, risks, and options for decision-making; balance scientific rigor, operational feasibility, and commercial value; serve as the single point of accountability for program operations, performance, and budget. Leadership & Team Development
Mentor project managers, foster ownership and high standards; demonstrate calm and confident leadership to handle ambiguity with discipline and purpose. Qualifications
Basic Qualification
MS or MBA in Life Sciences or related field Experience working on an oncology asset Experience in project management using PM principles (e.g., PMI/PMBOK), including risk management, planning, execution, scenario analysis, communication, and reporting Experience maintaining project plans, budgets, forecasts, and documentation in Planisware Preferred Qualification
Experience in drug development with focus on oncology program or portfolio management A minimum of 3 years' experience in life sciences consulting, specializing in strategic planning and project delivery within the pharmaceutical sector Proven track record leading large, cross-functional oncology programs (multi-asset or multi-region) Advanced program management tools (Planisware, MS Project, Smartsheet), risk modeling, budget/resource tracking Soft Skills: Executive presence, stakeholder influence, strategic communication, and ability to navigate ambiguity Skilled in leading project team meetings Proficient in preparing for governance reviews to support funding, resources, and project decisions What we offer
You will join a purpose-driven organization committed to uniting science, technology and talent to get ahead of disease together. You will have the chance to lead meaningful work, grow professionally and influence outcomes that matter to patients around the world. Ready to apply? If you are motivated to lead complex programs, develop people, and deliver measurable impact, we encourage you to apply. We welcome applicants from all backgrounds and are committed to inclusion. Based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, salary ranges: Cambridge/Waltham/Rockville/San Francisco: $203,775 to $339,625; other US locations: $185,250 to $308,750. Salaries depend on location, skills, experience, and market rate. This position offers an annual bonus and eligibility to participate in our long-term incentive program. Benefits include health care and other insurance, retirement, paid holidays, vacation, and paid caregiver/parental and medical leave. Please note: if salary ranges are not displayed for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit
GSK US Benefits Summary
to learn more about the comprehensive benefits program GSK offers US employees. Why GSK?
Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. We are committed to creating an environment where our people can thrive and focus on what matters most. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call. If your inquiry does not relate to adjustments, we will not be able to support you through these channels. We have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies: GSK does not accept referrals from employment businesses and/or employment agencies in respect of vacancies posted on this site. All employment businesses/agencies must contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring candidates. Without written authorization, actions by agencies are not binding on GSK. GSK may be required to capture and report expenses for US Licensed Healthcare Professionals in relation to interviews. For more information, visit the CMS site at openpaymentsdata.cms.gov.
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USA - Pennsylvania - Upper Providence, USA - Massachusetts - Boston Posted Date:
Feb 5 2026 Overview
Business Introduction: At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Position Summary: As the Senior Director of Program Management Oncology for a flagship oncology asset, you will be the driving force behind flawless execution—translating strategy into action and ensuring disciplined delivery of program milestones. You will shape critical decisions by influencing stakeholders through data-driven insights and external perspectives, while fostering a culture of accountability and agility. Your role demands operational rigor, proactive risk management, and the ability to challenge assumptions to accelerate progress without compromising quality or safety. Key Responsibilities
Acting as the Medicine Development Leader’s strategic partner and primary point of contact for the program’s Medicine Development Team (MDT), overseeing a complex, multi-tumor program—integrating clinical development, asset and evidence strategies into a unified vision. Lead all project management aspects of this high-visibility initiative, ensuring milestone delivery at pace while upholding quality and safety. Strategic Orchestration and Cross-Functional Leadership.
Integrate clinical, regulatory, CMC, and commercial strategies into a unified program plan; guide strategic discussions and encourage diverse viewpoints to reach actionable outcomes; leverage insights from external experts and benchmarks; maintain an overview of systems to identify dependencies and manage complexity. Demonstrate Critical Thinking
This requires questioning assumptions and exploring new approaches through insightful inquiries; simplify complex topics into actionable insights for senior leaders; work with Medicine Development Leaders to optimize asset strategy considering both business and patient needs. Agility Initiative, and Execution Excellence
Promote team adaptability to evolving data and priorities, lead scenario planning to minimize disruption while staying aligned with long-term objectives and clearly communicate changes to keep program goals in focus. Responsibilities
Take ownership of program execution, proactively resolve challenges, lead planning and risk management, track progress, identify opportunities for innovation and efficiency, and accelerate outcomes by streamlining decision-making and removing obstacles. Stakeholder Engagement and Facilitation Excellence
Engage with senior leaders, governance bodies, external partners, and subject matter experts; lead tailored meetings that enable decisive outcomes; cultivate trusted relationships and influence through credibility, data-driven insights, and composure; ensure program visibility through compelling storytelling and impactful dashboards. Governance, Communication and Executive Engagement
Facilitate governance interactions and translate complexity into clear, data-driven recommendations; summarize strategy, risks, and options for decision-making; balance scientific rigor, operational feasibility, and commercial value; serve as the single point of accountability for program operations, performance, and budget. Leadership & Team Development
Mentor project managers, foster ownership and high standards; demonstrate calm and confident leadership to handle ambiguity with discipline and purpose. Qualifications
Basic Qualification
MS or MBA in Life Sciences or related field Experience working on an oncology asset Experience in project management using PM principles (e.g., PMI/PMBOK), including risk management, planning, execution, scenario analysis, communication, and reporting Experience maintaining project plans, budgets, forecasts, and documentation in Planisware Preferred Qualification
Experience in drug development with focus on oncology program or portfolio management A minimum of 3 years' experience in life sciences consulting, specializing in strategic planning and project delivery within the pharmaceutical sector Proven track record leading large, cross-functional oncology programs (multi-asset or multi-region) Advanced program management tools (Planisware, MS Project, Smartsheet), risk modeling, budget/resource tracking Soft Skills: Executive presence, stakeholder influence, strategic communication, and ability to navigate ambiguity Skilled in leading project team meetings Proficient in preparing for governance reviews to support funding, resources, and project decisions What we offer
You will join a purpose-driven organization committed to uniting science, technology and talent to get ahead of disease together. You will have the chance to lead meaningful work, grow professionally and influence outcomes that matter to patients around the world. Ready to apply? If you are motivated to lead complex programs, develop people, and deliver measurable impact, we encourage you to apply. We welcome applicants from all backgrounds and are committed to inclusion. Based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, salary ranges: Cambridge/Waltham/Rockville/San Francisco: $203,775 to $339,625; other US locations: $185,250 to $308,750. Salaries depend on location, skills, experience, and market rate. This position offers an annual bonus and eligibility to participate in our long-term incentive program. Benefits include health care and other insurance, retirement, paid holidays, vacation, and paid caregiver/parental and medical leave. Please note: if salary ranges are not displayed for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit
GSK US Benefits Summary
to learn more about the comprehensive benefits program GSK offers US employees. Why GSK?
Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. We are committed to creating an environment where our people can thrive and focus on what matters most. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call. If your inquiry does not relate to adjustments, we will not be able to support you through these channels. We have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies: GSK does not accept referrals from employment businesses and/or employment agencies in respect of vacancies posted on this site. All employment businesses/agencies must contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring candidates. Without written authorization, actions by agencies are not binding on GSK. GSK may be required to capture and report expenses for US Licensed Healthcare Professionals in relation to interviews. For more information, visit the CMS site at openpaymentsdata.cms.gov.
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