Director, In Silico Discovery, CADD – San Diego, CA
Johnson & Johnson, San Diego, California, United States, 92189
Overview
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we innovate across the full spectrum of healthcare solutions to deliver breakthroughs of tomorrow and impact health for humanity. Job Function: Data Analytics & Computational Sciences Job Sub Function: Data Science Job Category: People Leader All Job Posting Locations: San Diego, California, United States of America Job Description: Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at jnj.com/innovative-medicine. Johnson & Johnson Innovative Medicine is currently seeking a Director, In Silico Discovery, Computer-Aided Drug Design (CADD) to join our In Silico Drug Discovery team in San Diego, CA.
We are seeking a creative, strategic and self-motivated leader to elevate our portfolio-facing CADD team. In the Director role, you will drive programs toward NMEs by strengthening partnerships across portfolio and global discovery chemistry teams and expanding the impact of cutting-edge computational design in small-molecule discovery. You will guide the La Jolla CADD team in applying both commercial and internally developed software solutions across the Johnson & Johnson portfolio. The ideal candidate is a highly collaborative and strategic leader passionate about advancing small-molecule design through computational innovation. This position offers the opportunity to join a diverse, global community of in silico scientists dedicated to delivering transformative medicines to patients. Responsibilities
Lead a high-performing portfolio-facing CADD team to drive computational design across the small-molecule portfolio with a vision of predict first. Develop and implement a comprehensive strategy to stay at the forefront of innovation in computational design for modalities including traditional small molecules, degraders, RIPTACS, GLUEs, peptides, and siRNA. Apply computational chemistry design and optimization strategies across our diverse portfolio; collaborate with In Silico Discovery and Global Discovery Chemistry teams to use predictive AI/ML tools for small molecule design and optimization. Mentor junior scientists and develop careers of CADD leaders; engage in industry consortia and represent In Silico Discovery in key initiatives. Evaluate and recommend acquisition or development of new technologies, including due diligence on partnering or M&A opportunities. Foster an inspiring, scientifically rigorous culture focused on continuous learning and collaboration; contribute to external publications and conferences as needed. Manage Managers, Supervisors, and/or individual contributors in a matrix environment; conduct performance management and career development conversations. Integrate Johnson & Johnson’s Credo and Leadership Imperatives into team goals and decision making. Professional Experience and Qualifications
Required: A PhD and a minimum of 10 years of experience in drug discovery with industry or related leadership experience. Demonstrated expertise in applied computation and small molecule drug discovery. Deep understanding of pharmaceutical discovery and optimization processes. Experience advancing initial hits toward NMEs; proven ability to build and lead teams. Preferred: Experience generating data visualizations (e.g., Spotfire, Vortex, Tableau, DataWarrior). Experience with multiple small molecule modalities (traditional SM, BRo5, degraders, RIPTAC, GLUE, peptides) and AI/ML approaches in drug discovery. Hands-on data curation, integration, mining, and analysis across large-scale datasets. Strong publication and/or patent record; ability to collaborate with external partners and multiple therapeutic areas. Excellent communication of complex data to diverse stakeholders; collaborative leadership style. Other
This position will be based on-site in San Diego, CA (La Jolla area) and may require up to approximately 20% travel both domestic and globally. No fully remote option available. Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by law. We actively seek protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to inclusive recruitment. If you are an individual with a disability and would like to request an accommodation, contact us via jnj.com/contact-us/careers. The anticipated base pay range for this position is $164,000 to $282,900. The Company offers competitive, performance-based compensation, and may include eligibility for annual bonuses. Benefits include medical, dental, vision, life insurance, disability coverage, and retirement plans. Vacation and leave policies are detailed at the company benefits site. Compensation information applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits per local market. #LI-SL #JNJDataScience #JNJIMRND-DS #LI-Hybrid Required Skills: Preferred Skills:
Advanced Analytics, Budget Management, Compliance Management, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Developing Others, Digital Fluency, Inclusive Leadership, Leadership, Program Management, Strategic Thinking, Succession Planning
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At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we innovate across the full spectrum of healthcare solutions to deliver breakthroughs of tomorrow and impact health for humanity. Job Function: Data Analytics & Computational Sciences Job Sub Function: Data Science Job Category: People Leader All Job Posting Locations: San Diego, California, United States of America Job Description: Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at jnj.com/innovative-medicine. Johnson & Johnson Innovative Medicine is currently seeking a Director, In Silico Discovery, Computer-Aided Drug Design (CADD) to join our In Silico Drug Discovery team in San Diego, CA.
We are seeking a creative, strategic and self-motivated leader to elevate our portfolio-facing CADD team. In the Director role, you will drive programs toward NMEs by strengthening partnerships across portfolio and global discovery chemistry teams and expanding the impact of cutting-edge computational design in small-molecule discovery. You will guide the La Jolla CADD team in applying both commercial and internally developed software solutions across the Johnson & Johnson portfolio. The ideal candidate is a highly collaborative and strategic leader passionate about advancing small-molecule design through computational innovation. This position offers the opportunity to join a diverse, global community of in silico scientists dedicated to delivering transformative medicines to patients. Responsibilities
Lead a high-performing portfolio-facing CADD team to drive computational design across the small-molecule portfolio with a vision of predict first. Develop and implement a comprehensive strategy to stay at the forefront of innovation in computational design for modalities including traditional small molecules, degraders, RIPTACS, GLUEs, peptides, and siRNA. Apply computational chemistry design and optimization strategies across our diverse portfolio; collaborate with In Silico Discovery and Global Discovery Chemistry teams to use predictive AI/ML tools for small molecule design and optimization. Mentor junior scientists and develop careers of CADD leaders; engage in industry consortia and represent In Silico Discovery in key initiatives. Evaluate and recommend acquisition or development of new technologies, including due diligence on partnering or M&A opportunities. Foster an inspiring, scientifically rigorous culture focused on continuous learning and collaboration; contribute to external publications and conferences as needed. Manage Managers, Supervisors, and/or individual contributors in a matrix environment; conduct performance management and career development conversations. Integrate Johnson & Johnson’s Credo and Leadership Imperatives into team goals and decision making. Professional Experience and Qualifications
Required: A PhD and a minimum of 10 years of experience in drug discovery with industry or related leadership experience. Demonstrated expertise in applied computation and small molecule drug discovery. Deep understanding of pharmaceutical discovery and optimization processes. Experience advancing initial hits toward NMEs; proven ability to build and lead teams. Preferred: Experience generating data visualizations (e.g., Spotfire, Vortex, Tableau, DataWarrior). Experience with multiple small molecule modalities (traditional SM, BRo5, degraders, RIPTAC, GLUE, peptides) and AI/ML approaches in drug discovery. Hands-on data curation, integration, mining, and analysis across large-scale datasets. Strong publication and/or patent record; ability to collaborate with external partners and multiple therapeutic areas. Excellent communication of complex data to diverse stakeholders; collaborative leadership style. Other
This position will be based on-site in San Diego, CA (La Jolla area) and may require up to approximately 20% travel both domestic and globally. No fully remote option available. Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by law. We actively seek protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to inclusive recruitment. If you are an individual with a disability and would like to request an accommodation, contact us via jnj.com/contact-us/careers. The anticipated base pay range for this position is $164,000 to $282,900. The Company offers competitive, performance-based compensation, and may include eligibility for annual bonuses. Benefits include medical, dental, vision, life insurance, disability coverage, and retirement plans. Vacation and leave policies are detailed at the company benefits site. Compensation information applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits per local market. #LI-SL #JNJDataScience #JNJIMRND-DS #LI-Hybrid Required Skills: Preferred Skills:
Advanced Analytics, Budget Management, Compliance Management, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Developing Others, Digital Fluency, Inclusive Leadership, Leadership, Program Management, Strategic Thinking, Succession Planning
#J-18808-Ljbffr