Principal Biostatistician (RWE, HEOR) - North America, Europe
Syneos Health, Inc., Virginia, Minnesota, United States, 55792
Job Details
Location:
USA-VA-Remote
Job ID:
25102670
Updated:
October 23, 2025
Overview Syneos Health® is a leading fully integrated biopharmaceutical solutions organization committed to accelerating customer success by translating clinical, medical, and commercial insights into outcomes.
About the Role Principal Biostatistician (RWE, HEOR) – North America, Europe. Responsible for the statistical aspects of clinical development, including real‑world evidence and health‑economics and outcomes research.
Job Responsibilities
Experience with a variety of real‑world data (eHR, registry studies, pharmacy data, etc.) and clinical trial data.
Experience with real‑world safety studies, including healthcare claims knowledge.
Apply propensity‑score matching, estimands, logistic regression, survival analysis, incident‑rate models.
Safety assessment skills: disproportionality analyses, statistical surveillance, safety risk modeling, data mining, AI/ML, signal detection.
Develop and review Statistical Analysis Plans (SAPs) and programming specifications for analysis datasets.
Generate randomization schedules and contribute to clinical study reports.
Collaborate with sponsor and study teams; provide independent review of statistical work.
Lead integrated analyses; attend regulatory agency meetings as needed.
Maintain well‑organized documentation and ensure inspection readiness.
Support business‑development activities and proposals where appropriate.
Provide statistical programming support and, when required, serve on DSMBs/DMCs.
General Experience and Qualifications
Graduate degree in biostatistics or related discipline.
Extensive experience in clinical trials or equivalent combination of education and experience.
Proficiency in programming (SAS preferred).
Strong knowledge of statistical design, analysis, regulatory guidelines, and programming techniques.
Experience with regulatory submissions preferred.
Excellent written and verbal communication skills; fluent in English.
Ability to read, write, speak, and understand English.
Minimal travel may be required.
Additional Information Legal compliance: Equal Opportunity Employer. Requested information for applicants with disabilities will be provided. All qualified applicants will receive consideration regardless of race, color, age, religion, marital status, ethnicity, gender identity, sexual orientation, veteran, or disability status.
Benefits Salary Range: $95,000 – $175,700. Benefits may include health, dental, vision, 401(k) match, Employee Stock Purchase Plan, commissions/bonus, paid time off, and more (subject to state regulations).
How to Apply Visit our careers site at
syneoshealth.com
for current opportunities.
#J-18808-Ljbffr
USA-VA-Remote
Job ID:
25102670
Updated:
October 23, 2025
Overview Syneos Health® is a leading fully integrated biopharmaceutical solutions organization committed to accelerating customer success by translating clinical, medical, and commercial insights into outcomes.
About the Role Principal Biostatistician (RWE, HEOR) – North America, Europe. Responsible for the statistical aspects of clinical development, including real‑world evidence and health‑economics and outcomes research.
Job Responsibilities
Experience with a variety of real‑world data (eHR, registry studies, pharmacy data, etc.) and clinical trial data.
Experience with real‑world safety studies, including healthcare claims knowledge.
Apply propensity‑score matching, estimands, logistic regression, survival analysis, incident‑rate models.
Safety assessment skills: disproportionality analyses, statistical surveillance, safety risk modeling, data mining, AI/ML, signal detection.
Develop and review Statistical Analysis Plans (SAPs) and programming specifications for analysis datasets.
Generate randomization schedules and contribute to clinical study reports.
Collaborate with sponsor and study teams; provide independent review of statistical work.
Lead integrated analyses; attend regulatory agency meetings as needed.
Maintain well‑organized documentation and ensure inspection readiness.
Support business‑development activities and proposals where appropriate.
Provide statistical programming support and, when required, serve on DSMBs/DMCs.
General Experience and Qualifications
Graduate degree in biostatistics or related discipline.
Extensive experience in clinical trials or equivalent combination of education and experience.
Proficiency in programming (SAS preferred).
Strong knowledge of statistical design, analysis, regulatory guidelines, and programming techniques.
Experience with regulatory submissions preferred.
Excellent written and verbal communication skills; fluent in English.
Ability to read, write, speak, and understand English.
Minimal travel may be required.
Additional Information Legal compliance: Equal Opportunity Employer. Requested information for applicants with disabilities will be provided. All qualified applicants will receive consideration regardless of race, color, age, religion, marital status, ethnicity, gender identity, sexual orientation, veteran, or disability status.
Benefits Salary Range: $95,000 – $175,700. Benefits may include health, dental, vision, 401(k) match, Employee Stock Purchase Plan, commissions/bonus, paid time off, and more (subject to state regulations).
How to Apply Visit our careers site at
syneoshealth.com
for current opportunities.
#J-18808-Ljbffr