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Mansueto Ventures is home to two of the most iconic and vibrant brands in business publishing: Inc. and Fast Company. Every day, the content, awards, and events produced help entrepreneurs and innovators succeed by providing useful insights, sparking essential conversations, and offering much-needed inspiration.

Inc. is the voice of the American entrepreneur, inspiring and documenting the risk-takers and ultra-driven go-getters who represent the most dynamic force in the American economy.
Fast Company is the world’s leading business media brand, focusing on innovation in technology, leadership, and design to inspire readers to shape the future of business.

","New York, NY","coloredLogo","logoAttachment","thumbnail","thumbnailAttachment","hexCode","#080D0C","headline","Publisher of Inc. and Fast Company, empowering innovators and entrepreneurs.","/companies/mansueto-ventures-careers","hasJobSubmission","isSavedJob","similarJobs",[510,524,531,537,545],{"_429":428,"_434":511,"_452":453,"_444":512,"_243":513,"_441":514,"_427":428,"_111":515,"_431":194,"_433":194,"_454":453,"_442":516,"_425":517,"_455":518,"_430":115,"_476":519,"_460":520,"_478":515,"_479":516,"_481":521,"_483":522,"_485":523},["D",1770897600000],"Amgen SA","A leading biotechnology firm is seeking a Therapeutic Area Head, Safety – Hematology/Oncology who will serve as the safety expert for Heme-Onc products. The role includes managing teams, overseeing safety strategy, and ensuring regulatory compliance. The ideal candidate holds an MD or DO, has significant leadership experience, and a strong background in Hematology/Oncology. This position offers competitive compensation and substantial benefits, aimed at fostering professional growth.\n#J-18808-Ljbffr\n","A leading biotechnology firm is seeking a Therapeutic Area Head, Safety – Hematology/Oncology who will serve as the safety expert for Heme-Onc prod...","Global Hematology/Oncology Safety — Executive Director","Thousand Oaks, California, United States, 91362",["B","2540012094"],"Work at Amgen SA","6 days ago","/jobs/2540012094-global-hematology-oncology-safety-executive-director","/jobs?keyword=Amgen+SA","/jobs?location=Thousand+Oaks%2C+California%2C+United+States%2C+91362","/jobs?keyword=Global+Hematology%2FOncology+Safety+%E2%80%94+Executive+Director",{"_429":428,"_434":525,"_452":453,"_444":445,"_243":438,"_441":438,"_427":428,"_111":437,"_431":432,"_433":194,"_454":453,"_442":526,"_425":527,"_455":456,"_430":115,"_476":528,"_460":529,"_478":437,"_479":526,"_481":482,"_483":530,"_485":486},["D",1771372800000],"None, None, US",["B","2619502396"],"1 days ago","/jobs/2619502396-executive-medical-director-global-safety-hematology-oncology","/jobs?location=None%2C+None%2C+US",{"_429":428,"_434":532,"_452":453,"_444":445,"_243":438,"_441":438,"_427":428,"_111":533,"_431":432,"_433":194,"_454":453,"_442":443,"_425":534,"_455":456,"_430":115,"_476":528,"_460":535,"_478":533,"_479":443,"_481":482,"_483":484,"_485":536},["D",1771372800000],"Product Quality Director - Synthetics",["B","2619506002"],"/jobs/2619506002-product-quality-director-synthetics","/jobs?keyword=Product+Quality+Director+-+Synthetics",{"_429":428,"_434":538,"_452":453,"_444":445,"_243":539,"_441":540,"_427":428,"_111":541,"_431":432,"_433":194,"_454":453,"_442":443,"_425":542,"_455":456,"_430":115,"_476":528,"_460":543,"_478":541,"_479":443,"_481":482,"_483":484,"_485":544},["D",1771372800000],"

In this vital role you will lead Amgens strategy and execution for Reinforcement Learning from Human Feedback (RLHF) and related reinforcement learning approaches across R&D, medical, operations, and commercial use cases. You will design, implement, Director, Associate, Computer Science, Data Engineer, Systems, IT, Technology

","

In this vital role you will lead Amgens strategy and execution for Reinforcement Learning from Human Feedback (RLHF) and related reinforcement l...","Associate Director, Reinforcement Learning (ML)",["B","2620489363"],"/jobs/2620489363-associate-director-reinforcement-learning-ml","/jobs?keyword=Associate+Director%2C+Reinforcement+Learning+%28ML%29",{"_429":428,"_434":546,"_452":453,"_444":512,"_243":547,"_441":548,"_427":428,"_111":549,"_431":194,"_433":194,"_454":453,"_442":516,"_425":550,"_455":518,"_430":115,"_476":551,"_460":552,"_478":553,"_479":516,"_481":521,"_483":522,"_485":554},["D",1770555600000],"At Amgen, if you feel like you are a part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Live\nWhat you will do\nLet’s do this. Let’s change the world. As we increase our investment in discovery research and early pipeline development, this role is critical to drive commercial strategy at the earliest stages of innovation. This position requires a leader who understands the intersection of science, strategy, and commercial execution—ensuring that Amgen’s early-stage investments are positioned for long-term success.

The Executive Director (ED), Disease Areas Strategy Lead (DASL) for OaR will play a pivotal role in shaping the future of Amgen’s portfolio by providing commercial insights into early-stage research, pipeline programs, and external business development opportunities.

In this role you will be responsible for the following

Partnering with Senior Leadership to define Amgen’s early pipeline commercial strategy to ensure investments in research and early development align with long-term business objectives and patient needs within OaR

Partnering closely with R&D, global marketing, and corporate development teams to assess external innovation and business development opportunities, ensuring alignment with Amgen’s portfolio strategy

Supporting portfolio investment decisions in coordination with the Enterprise Portfolio Governance function

Developing commercial frameworks and business cases to inform progression decisions for early-stage assets, integrating insights from market dynamics, patient needs, and competitive intelligence

Building a best-in-class commercial function for early pipeline strategy, ensuring Amgen maintains a leadership position in bringing first-in-class and best-in-class therapies to market

Key activities and accountabilities include the following

Early Pipeline Strategy & Portfolio Prioritization\nLearns frameworks for evaluating and prioritizing early-stage assets; assess commercial viability and differentiation of assets in early development, ensuring alignment with evolving market needs and payer landscapes

Shape long-term portfolio strategy in collaboration with R&D, finance, and business development teams

Commercial Partnership with Research & Early Development\nProvide commercial input to research-stage investment decisions, ensuring a clear path to differentiated and commercially viable products

Collaborate with R&D to develop target product profiles (TPPs) that reflect strong commercial positioning

Business development & External Innovation\nPartner with Amgen’s Business Development team to evaluate in-licensing, partnerships, and acquisitions for early-stage assets

Conduct commercial due diligence on external opportunities, integrating scientific innovation with market insights

Leadership & Team Development\nLead the cross functional Therapy Area Strategy group focused on early pipeline and business development

Establish strong cross-functional partnerships with R&D, corporate strategy, finance, and global marketing teams

Enterprise Portfolio Governance & Investment Strategy\nPlay a key role in the Portfolio Governance process, ensuring that commercial insights drive R&D investment decisions

Align early-stage investments with Amgen’s strategic growth objectives and therapeutic area priorities

Win\nWhat we expect of you\nWe are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications.

Basic Qualifications

Doctorate degree & 6 years of commercial experience OR

Master’s degree & 10 years of commercial experience OR

Bachelor’s degree & 12 years of commercial experience AND

6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

A minimum of 3 years of relevant experience either via a scientific degree or position held in a scientific field

Preferred Qualifications

Master of Business Administration

MD or PhD in a life sciences-related field (e.g., molecular biology, immunology, pharmacology)

12+ years of commercial experience in the biopharmaceutical industry, with time spent in marketing, commercial strategy, and/or pipeline development

Experience in management consulting (McKinsey, Bain, BCG) focused on strategy, commercial development, and business development in the life sciences industry

Experience in commercial development for pipeline assets, including product positioning, market assessment, and competitive analysis

Experience in business development, including due diligence and partnership evaluations

Experience working in cross-functional leadership roles across commercial and R&D teams

Track record in enterprise portfolio strategy, including investment decision-making and pipeline prioritization

Executive leadership and people management skills with a proven ability to develop and mentor high-performing teams

Prior biopharmaceutical leadership experience overseeing commercial strategy, commercial development, and marketing functions

Deep knowledge of global biopharma market dynamics, payer trends, and competitive landscapes

Experience engaging with executive leadership and board-level stakeholders on commercial and R&D investment decisions

Analytical, financial, and strategic thinking skills with the ability to translate complex data into actionable insights

Thrive\nWhat you can expect of us\nAs we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. The annual base salary range for this opportunity in the U.S. $315,211 to $362,906. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans and bi-annual company-wide shutdowns

Flexible work models, including remote work arrangements, where possible

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship is not guaranteed for this role.

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