Germany – PhD in Analytical Sciences at Leibniz Institute for Analytical Science
PhDFinder, Institute, NC, United States
University:
Leibniz Institute for Analytical Sciences – ISAS – e.V. Location:
Dortmund, North Rhine-Westphalia, Germany Deadline:
18 April 2026 Field:
Biochemistry, Molecular Biology, Analytical Chemistry, Life Sciences, Bioinformatics
Overview The Leibniz Institute for Analytical Sciences (ISAS) in Dortmund offers a part‑time (65 %) PhD position in the Research Group Biofluorescence. Focus: profiling cellular components of tissue microenvironments (TMEs) in healthy and inflamed states using mass‑spectrometry‑based multi‑omics techniques. The role aims to advance precision medicine by uncovering cellular heterogeneity and identifying novel biomarkers.
Project Details
Develop automated sample‑preparation pipelines for proteomic analyses of human and mouse immune cells isolated from TME at single‑cell or few‑cell level.
Design and implement high‑throughput LC‑MS/MS workflows capable of analysing proteomes of 500–1,000 single cells or several small cell preparations per day.
Collaborate closely with computational teams to integrate multi‑omics data and classify distinct cell populations.
Support the development of computational frameworks to predict metabolic activity of cell populations based on omics data.
Conduct phenotypic assays to validate cellular heterogeneity.
Analyse complex datasets and communicate findings within an interdisciplinary team comprising experts in natural sciences, life sciences, computer science, and medicine.
Present research outcomes at lab meetings, collaboration partners, and at national and international conferences.
Contribute to the preparation of manuscripts for publication in peer‑reviewed international journals.
Candidate Profile
Master’s, Diploma, or equivalent degree in biochemistry, chemistry, molecular biology, or a related scientific field.
Previous experience in protein biochemistry and LC/MS‑based mass spectrometry.
Experience in omics data analysis using relevant software.
Familiarity with R and Python programming languages is advantageous but not mandatory.
Strong presentation and scientific writing skills.
Proactive, independent, and solution‑oriented approach to research.
Excellent command of English, both spoken and written.
Benefits / Opportunities The position offers a salary in accordance with the German TV‑L scale, reflecting competitive academic employment standards. ISAS provides state‑of‑the‑art facilities, an international environment, career‑development workshops, and opportunities for professional networking at conferences. International applicants receive support with accommodation, administrative procedures, and integration into the German academic environment.
Application Process The application deadline is 18 April 2026. Applications must be submitted via the ISAS applicant portal. For further details, refer to the official advertisement: https://www.nature.com/naturecareers/job/12856713/phd-candidate-m-f-d-/.
Equal Opportunity Statement ISAS is committed to equal opportunity and particularly encourages applications from women and individuals with disabilities. International applicants are supported in finding accommodation and navigating administrative processes.
FAQ
What are the main research areas at ISAS? ISAS focuses on developing advanced analytical methods for health research, particularly in precision medicine, involving biology, chemistry, computer science, medicine, pharmacology, and physics.
What is the significance of studying tissue microenvironments at single‑cell resolution? It allows researchers to uncover cellular and molecular heterogeneity, crucial for understanding disease mechanisms and developing targeted therapies.
What support is available for international PhD students at ISAS? Assistance with accommodation, administrative procedures, integration, training, professional development, and access to advanced research infrastructure.
Is prior experience in programming languages like R or Python mandatory? Advantages only; not mandatory.
What are the benefits of pursuing a PhD in Germany? High research standards, robust funding, excellent social benefits, and a vibrant academic community.
How long is the duration of the PhD position? 3.5 years on a part‑time (65 %) basis.
What salary can I expect as a PhD student at ISAS? Based on the German TV‑L scale, competitive and including social benefits.
Are there opportunities for professional development and networking? Yes, participation in international conferences, workshops, training programs, and broad professional networks.
#J-18808-Ljbffr
Leibniz Institute for Analytical Sciences – ISAS – e.V. Location:
Dortmund, North Rhine-Westphalia, Germany Deadline:
18 April 2026 Field:
Biochemistry, Molecular Biology, Analytical Chemistry, Life Sciences, Bioinformatics
Overview The Leibniz Institute for Analytical Sciences (ISAS) in Dortmund offers a part‑time (65 %) PhD position in the Research Group Biofluorescence. Focus: profiling cellular components of tissue microenvironments (TMEs) in healthy and inflamed states using mass‑spectrometry‑based multi‑omics techniques. The role aims to advance precision medicine by uncovering cellular heterogeneity and identifying novel biomarkers.
Project Details
Develop automated sample‑preparation pipelines for proteomic analyses of human and mouse immune cells isolated from TME at single‑cell or few‑cell level.
Design and implement high‑throughput LC‑MS/MS workflows capable of analysing proteomes of 500–1,000 single cells or several small cell preparations per day.
Collaborate closely with computational teams to integrate multi‑omics data and classify distinct cell populations.
Support the development of computational frameworks to predict metabolic activity of cell populations based on omics data.
Conduct phenotypic assays to validate cellular heterogeneity.
Analyse complex datasets and communicate findings within an interdisciplinary team comprising experts in natural sciences, life sciences, computer science, and medicine.
Present research outcomes at lab meetings, collaboration partners, and at national and international conferences.
Contribute to the preparation of manuscripts for publication in peer‑reviewed international journals.
Candidate Profile
Master’s, Diploma, or equivalent degree in biochemistry, chemistry, molecular biology, or a related scientific field.
Previous experience in protein biochemistry and LC/MS‑based mass spectrometry.
Experience in omics data analysis using relevant software.
Familiarity with R and Python programming languages is advantageous but not mandatory.
Strong presentation and scientific writing skills.
Proactive, independent, and solution‑oriented approach to research.
Excellent command of English, both spoken and written.
Benefits / Opportunities The position offers a salary in accordance with the German TV‑L scale, reflecting competitive academic employment standards. ISAS provides state‑of‑the‑art facilities, an international environment, career‑development workshops, and opportunities for professional networking at conferences. International applicants receive support with accommodation, administrative procedures, and integration into the German academic environment.
Application Process The application deadline is 18 April 2026. Applications must be submitted via the ISAS applicant portal. For further details, refer to the official advertisement: https://www.nature.com/naturecareers/job/12856713/phd-candidate-m-f-d-/.
Equal Opportunity Statement ISAS is committed to equal opportunity and particularly encourages applications from women and individuals with disabilities. International applicants are supported in finding accommodation and navigating administrative processes.
FAQ
What are the main research areas at ISAS? ISAS focuses on developing advanced analytical methods for health research, particularly in precision medicine, involving biology, chemistry, computer science, medicine, pharmacology, and physics.
What is the significance of studying tissue microenvironments at single‑cell resolution? It allows researchers to uncover cellular and molecular heterogeneity, crucial for understanding disease mechanisms and developing targeted therapies.
What support is available for international PhD students at ISAS? Assistance with accommodation, administrative procedures, integration, training, professional development, and access to advanced research infrastructure.
Is prior experience in programming languages like R or Python mandatory? Advantages only; not mandatory.
What are the benefits of pursuing a PhD in Germany? High research standards, robust funding, excellent social benefits, and a vibrant academic community.
How long is the duration of the PhD position? 3.5 years on a part‑time (65 %) basis.
What salary can I expect as a PhD student at ISAS? Based on the German TV‑L scale, competitive and including social benefits.
Are there opportunities for professional development and networking? Yes, participation in international conferences, workshops, training programs, and broad professional networks.
#J-18808-Ljbffr