Associate Director, Drug Substance Development & Manufacturing
Scorpion Therapeutics, Boston, MA, United States
Overview
The Organization: Entrada Therapeutics is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by engaging intracellular targets. Our lead oligonucleotide programs are in development for Duchenne muscular dystrophy (DMD) exon skipping and a collaboration with Vertex on a myotonic dystrophy type 1 (DM1) program. 2026 is a catalyst-rich year with multiple clinical data readouts and the expectation of several clinical-stage programs across the U.K., EU, and U.S. We are a tight-knit team focused on delivering impactful therapies and growing with colleagues who want to get things done and improve patients’ lives. The Perfect Addition to Our Team: You are a motivated, resourceful, and enthusiastic Drug Substance Development & Manufacturing expert with experience in peptide and/or oligonucleotide late-stage process development, GMP manufacturing, and supply chain of drug substances. You excel with minimal supervision in a collaborative matrix environment and interact across Chemistry, Analytical, Drug Product, Quality, and CDMOs. The Opportunity: The Associate Director of Drug Substance Development and Manufacturing will lead late-stage drug substance development for Entrada’s pipeline, supporting development activities for clinical and commercial batches and ensuring validation parameters for manufacturing batches.
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The Organization: Entrada Therapeutics is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by engaging intracellular targets. Our lead oligonucleotide programs are in development for Duchenne muscular dystrophy (DMD) exon skipping and a collaboration with Vertex on a myotonic dystrophy type 1 (DM1) program. 2026 is a catalyst-rich year with multiple clinical data readouts and the expectation of several clinical-stage programs across the U.K., EU, and U.S. We are a tight-knit team focused on delivering impactful therapies and growing with colleagues who want to get things done and improve patients’ lives. The Perfect Addition to Our Team: You are a motivated, resourceful, and enthusiastic Drug Substance Development & Manufacturing expert with experience in peptide and/or oligonucleotide late-stage process development, GMP manufacturing, and supply chain of drug substances. You excel with minimal supervision in a collaborative matrix environment and interact across Chemistry, Analytical, Drug Product, Quality, and CDMOs. The Opportunity: The Associate Director of Drug Substance Development and Manufacturing will lead late-stage drug substance development for Entrada’s pipeline, supporting development activities for clinical and commercial batches and ensuring validation parameters for manufacturing batches.
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