Zone Director - Central

Pharvaris is a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to address bradykinin-mediated angioedema. We are expanding our U.S. Commercial team and are looking for a

Zone Director

to join our team and report to the VP, Head of Sales & Marketing. The Zone Director will hire and lead a team of approximately 8-10 Area Business Managers (ABMs) for the launch of Deucrictibant IR & XR in the rare disease market. The Zone Director will build and lead a high-performance sales team, drive market adoption, and execute a best-in-class commercial strategy in a competitive landscape. The ideal candidate is a proven leader who can inspire, coach, and hold a team accountable for results while maintaining a deep understanding of physician practice operations, payer dynamics, and competitive differentiation.

Location
Pharvaris promotes a flexible hybrid work environment. This remote/hybrid role requires being in the United States and able to support one of the zones: Northeast, Southeast, West, or Central.

Responsibilities

Sales Leadership & Performance Management

Hire, develop, and lead a team of 8-10 Area Business Managers (ABMs)

Establish and maintain a high-performance sales culture driven by accountability, execution, and competition

Ensure team members are set up for success and consistently meet or exceed sales targets

Serve as a front-line leader, modeling best-in-class sales execution and objection handling

Strategic Market Execution

Develop and execute territory strategies that maximize market penetration and growth

Translate corporate and brand strategy into tactical field execution

Feed field insights back to cross-functional teams to optimize strategy

Leverage data and analytics tools to drive business decisions and maximize field performance

KOL & Stakeholder Engagement

Establish and maintain long-lasting relationships with Key Opinion Leaders (KOLs) and top prescribers

Partner with Market Access, Patient Services, and Medical Affairs to optimize payer pull-through and patient access

Develop strategies to increase disease awareness and brand adoption in targeted accounts

Field Sales Training & Team Development

Facilitate sales training programs focused on disease state knowledge, clinical differentiation, and reimbursement dynamics

Conduct field coaching and real-time training, ensuring ABMs are market-ready

Lead by example, demonstrating coaching skills in live customer engagements

Sales Force Effectiveness & Execution Discipline

Ensure all sales activities are executed with precision, consistency, and compliance

Utilize CRM (Salesforce) and field systems to track performance, measure KPIs, and drive accountability

Monitor and refine team execution based on real-time market insights and competitive intelligence

Ownership Mentality & Travel Requirements

Own the number—demonstrate accountability for regional performance

Up to 70% travel

Foster a culture of resilience, adaptability, and problem-solving under pressure

Requirements

Bachelor’s degree required

Proven rare disease sales leadership experience (minimum 3+ years in leadership roles)

Track record of hiring, developing, and managing successful sales teams

Strong business acumen with deep understanding of market access, payer dynamics, and reimbursement

Exceptional KOL & stakeholder engagement skills—ability to build deep, strategic relationships

Competitive, high-energy, and execution-focused mindset

Ability to model best-in-class sales skills and coach teams to excellence

Strong communication and influence skills—comfortable leading from the front

Field-first leadership approach—willing to travel and lead in-market

Comfortable working in a fast-paced, evolving environment with an entrepreneurial mindset

Pharvaris is committed to fair and equitable compensation practices. The base salary range for this role is $210,000-$245,000 per year. Actual compensation depends on depth of experience, skill set, overall performance, and education. This role offers a competitive total rewards package including equity and time off. We encourage candidates motivated by the full opportunity and mission to apply.

Note
Are you eligible to work in the United States without visa sponsorship? Do you have a bachelor’s degree? Do you have a valid driver’s license? What are your compensation expectations?

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