Vice President US Marketing

Company Overview
Ascendis Pharma is a global biopharmaceutical company focused on applying its proprietary TransCon® technology platform to develop therapies with the potential to improve treatment safety, efficacy, tolerability, and convenience. Guided by its core values of Patients, Science, and Passion, the company develops TransCon-based therapies designed to address unmet medical needs. Ascendis is advancing programs in Endocrinology Rare Disease and Oncology, while also collaborating with partners on the development of TransCon-based products in additional therapeutic areas and geographic markets. The company is headquartered in Copenhagen, Denmark, with research and development facilities in Germany and offices across Europe and the United States.

As of March 31, 2026, Ascendis Pharma reported €573.0 million in cash and cash equivalents, compared with €616.0 million as of December 31, 2025, according to the company's first quarter 2026 financial results.

Job Summary
Ascendis Pharma is seeking a

Vice President US Marketing

to lead U.S. marketing across its growing endocrine rare disease portfolio. Reporting to the Joe Kelly, SVP, U.S. Endocrinology Franchise Head, this individual will be responsible for the strategic leadership, development, and execution of marketing across three commercial brands in the U.S., including YORVIPATH® (hypoparathyroidism), SKYTROFA® (growth hormone deficiency), and YUVIWEL® (achondroplasia).

This leader will play a critical role in maximizing the performance of currently marketed products while preparing for and executing future growth opportunities, ensuring strong portfolio positioning, differentiated brand strategies, and sustained revenue growth. The VP will oversee both brand and portfolio strategy, aligning cross-functional teams to deliver impact across healthcare providers, patients, and payers in the U.S. market.

Essential Functions and Duties

Develop and lead U.S. portfolio and brand strategies across Ascendis’ commercial endocrine assets, including YORVIPATH®, SKYTROFA®, and YUVIWEL®

Provide leadership for the Marketing team including organizational design, staffing, developing and mentoring the team.

Drive end-to-end marketing strategy and execution, ensuring alignment with corporate objectives and U.S. commercial priorities

Oversee brand planning and lifecycle management across all three products

Develop and execute integrated tactical plans to maximize market share, patient adoption, and revenue growth across the portfolio

Partner closely with Market Access to ensure aligned strategies on pricing, reimbursement, and distribution in the U.S. market

Ensure Sales teams are equipped with compelling messaging, tools, and resources tailored to diverse stakeholder groups (HCPs, patients, payers)

Establish KPIs and performance metrics to evaluate brand and portfolio success, and adjust strategies based on insights

Collaborate cross-functionally with Medical Affairs, Regulatory, Clinical Development, Market Access, Legal/Compliance, and Commercial Operations to ensure aligned execution

Lead competitive intelligence efforts and assess implications for portfolio positioning and strategy

Key contributor to forecasting and long-range planning for the U.S. portfolio, identifying key growth drivers and risks

Build and maintain relationships with key opinion leaders, advocacy groups, and industry stakeholders to inform strategy and enhance disease awareness

Support ongoing lifecycle expansion opportunities and potential future indications across the portfolio

Ensure all marketing activities are executed in full compliance with U.S. regulatory and legal requirements

Skills and Experience

BA/BS required; MBA or advanced degree strongly preferred

15+ years of experience in the biopharmaceutical industry

Significant experience in U.S. marketing leadership roles, including multi-brand or portfolio responsibility

Strong background across Marketing, Sales, Market Access, and/or Commercial Operations

Demonstrated success in product launches and lifecycle management, ideally in rare disease and/or endocrinology

Proven ability to lead complex, cross-functional teams in a matrixed organization

Strong strategic thinking with the ability to translate into clear, executable plans

Excellent communication and leadership presence, with the ability to influence senior stakeholders

Highly analytical and results-oriented mindset

Deep understanding of the U.S. healthcare, reimbursement, and regulatory environment

Demonstrated commitment to ethics, compliance, and patient-centricity

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