Pharmacology Research Scientist-(Immunology)
Council of State and Territorial Epidemiologists, Boston, MA, United States
Job Description
The Pharmacology Research Scientist works with a high degree of independence and is adept at conceptually outlining in vivo and in vitro immunological studies to design, execute and interpret assays to study the action of compounds on disease biology. Completes work in a resourceful, self-sufficient manner and is able to design alternative approaches to achieve desired outcomes. Keeps current on the scientific literature relevant to scientific methodology or field(s) of technical expertise. This level captures both the Research organization's entry level for staff with a research doctoral degree (PhD) and the advanced experimental expert leading one or more critical laboratory functions with high impact on drug discovery projects.
Key Duties and Responsibilities
Design and conduct elaborate, conceptually connected, multi-component immunological and pharmacological experiments
Collate and interpret complex data systematically and synthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities
Exercises solid judgment to prioritize studies, considering feasibility and Project impact
Performs advanced and/or complex experimental troubleshooting
Scours relevant scientific literature and routinely incorporate new insights into research activities
Identifies, prioritizes and introduces relevant emerging technologies in field of expertise to advance the existing technology platforms and create/maintain a competitive advantage
Explores the feasibility of applying new scientific principles/concepts or implements and validates novel experimental approaches and technologies to achieve project goals
Independently prepares study presentations and presents experimental conclusions at internal Group/Department or Project Team research meetings
Contributes significantly to patent and/or publication preparation
Performs other duties as assigned
Knowledge and Skills
Demonstrated ability to design, execute and interpret complex immunological and pharmacological in vivo and in vitro experiments, to measure the action of compounds in disease relevant contexts
Expertise in the development and optimization of complex in vivo models of inflammation or autoimmune diseases
Advanced skills in immunological techniques, such as flow cytometry, immunophenotyping, and in vitro/ex vivo cellular assays, to characterize immune responses and compound efficacy.
Proficiency in a wide range of in vivo techniques, including routes of administration, blood/tissue harvesting, and processing for cellular/molecular analyses of immune responses and target engagement in immune models
A broad working knowledge of fundamental immunology and pharmacology principles
Demonstrates astute understanding of own discipline and the relevant literature
Maintains a high level of knowledge related to current developments in the scientific Project field
Displays proven productivity and experimental creativity, and effective dissemination of ideas
Demonstrates effective, self-sufficient communication skills, especially in peer-directed presentations
Demonstrates awareness of other Project-related disciplines and an understanding of general concepts and some experimental detail within those areas
Education and Experience
Ph.D. Immunology, pharmacology or related discipline and 0-3 years of relevant post-doctoral employment experience
Master's degree and 3+ years of relevant employment experience
Bachelor's degree and 6+ years of relevant employment experience
Pay Range $110,900 - $166,300
Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation On-Site Designated
Flex Eligibility Status In this
On-Site
designated role, you will work
five days per week on-site
with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
Company Information Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
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Key Duties and Responsibilities
Design and conduct elaborate, conceptually connected, multi-component immunological and pharmacological experiments
Collate and interpret complex data systematically and synthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities
Exercises solid judgment to prioritize studies, considering feasibility and Project impact
Performs advanced and/or complex experimental troubleshooting
Scours relevant scientific literature and routinely incorporate new insights into research activities
Identifies, prioritizes and introduces relevant emerging technologies in field of expertise to advance the existing technology platforms and create/maintain a competitive advantage
Explores the feasibility of applying new scientific principles/concepts or implements and validates novel experimental approaches and technologies to achieve project goals
Independently prepares study presentations and presents experimental conclusions at internal Group/Department or Project Team research meetings
Contributes significantly to patent and/or publication preparation
Performs other duties as assigned
Knowledge and Skills
Demonstrated ability to design, execute and interpret complex immunological and pharmacological in vivo and in vitro experiments, to measure the action of compounds in disease relevant contexts
Expertise in the development and optimization of complex in vivo models of inflammation or autoimmune diseases
Advanced skills in immunological techniques, such as flow cytometry, immunophenotyping, and in vitro/ex vivo cellular assays, to characterize immune responses and compound efficacy.
Proficiency in a wide range of in vivo techniques, including routes of administration, blood/tissue harvesting, and processing for cellular/molecular analyses of immune responses and target engagement in immune models
A broad working knowledge of fundamental immunology and pharmacology principles
Demonstrates astute understanding of own discipline and the relevant literature
Maintains a high level of knowledge related to current developments in the scientific Project field
Displays proven productivity and experimental creativity, and effective dissemination of ideas
Demonstrates effective, self-sufficient communication skills, especially in peer-directed presentations
Demonstrates awareness of other Project-related disciplines and an understanding of general concepts and some experimental detail within those areas
Education and Experience
Ph.D. Immunology, pharmacology or related discipline and 0-3 years of relevant post-doctoral employment experience
Master's degree and 3+ years of relevant employment experience
Bachelor's degree and 6+ years of relevant employment experience
Pay Range $110,900 - $166,300
Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation On-Site Designated
Flex Eligibility Status In this
On-Site
designated role, you will work
five days per week on-site
with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
Company Information Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
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