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Principal Mechanical Engineer II (Life Sciences)

Dawar Consulting, Santa Clara, CA, United States


Principal Mechanical Engineer III (Life Sciences) Santa Clara, United States | Posted on 02/10/2026

Our client, a world leader in biotechnology and life sciences, is looking for a " Principal Mechanical Engineer III " based out in

Santa Clara, CA .

Job Duration:

Long Term Contract (Possibility Of Extension)

Pay Rate :

$85-$92/hr on W2

Company Benefits:

Medical, Dental, Vision, Paid Sick leave, 401K

Job Summary:

You will lead the design and development of next-generation DNA sequencing instrumentation. This is a hands‑on, senior‑level role focused on solving complex mechanical challenges at the core of highly integrated life science systems.

Responsibilities

Lead end‑to‑end mechanical design of complex sub‑systems, including electro‑mechanical, fluidic, pneumatic, and thermal components

Design mechanisms for automated reagent and flow cell handling, sealing, and clamping

Architect precision thermal control systems (heating, cooling, sensors, condensation control)

Collaborate cross‑functionally with electrical, systems, consumables, materials, and assay teams

Support system integration, verification, and troubleshooting as the technical owner

Drive design reviews, manage technical trade‑offs, and deliver design documentation (CAD, drawings, specs)

Contribute to future system architecture and technology strategy

Skills / Qualifications

PhD + 5 years, MS + 10 years, or BS + 10+ years in Mechanical Engineering, Bioengineering, or related field

Strong expertise in fluidics systems (pumps, valves, tubing, sensors)

Proven experience in thermal management and precision temperature control

Advanced proficiency in 3D CAD (SolidWorks preferred)

Experience with prototyping, testing, and manufacturing processes (machining, injection molding, 3D printing)

Familiarity with Python, LabVIEW, or similar tools for device control and data acquisition

Preferred Qualifications

Experience with NGS or genomics instrumentation

Use of CFD / FEA to guide design decisions

Demonstrated technical leadership and mentoring experience

Mechanical Design, Fluidics, Thermal Management, 3D CAD

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