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Executive Director, Payer Accounts (EDG-2026028)

Edgewise Therapeutics, All Saints Village, MO, United States


Executive Director, Payer Accounts About Edgewise Therapeutics: At Edgewise, we are on a mission to discover new medicines that improve the lives of patients facing serious muscle disease. Our intimate knowledge of muscle biology and biophysics along with our ability to identify and design muscle‑specific precision small molecules have enabled us to rapidly advance our skeletal muscle and cardiac muscle product candidates into the clinic while also building a robust pre‑clinical pipeline. With this focus on therapeutics designed to protect and improve muscle health, our goal is to dramatically enhance the lives of people living with progressive muscle disorders.

About the Position The Executive Director, Payer Accounts position is an opportunity for an innovative, proactive market access leader to join Edgewise in a period of rapid commercial growth. We are preparing for the launches of sevasemten in rare neuromuscular diseases and EDG‑7500 in serious cardiac muscle diseases. A successful candidate will have deep, partnership‑centric relationships at top corporate
ational accounts, a track record of engaging customers pre‑ and post‑pivotal data and PDUFA, team leadership experience, and a demonstrated ability to achieve rapid, high‑quality access with and without contracting. This “player/coach” role will have individual responsibility for a “big‑3” account, develop the strategy to engage commercial and government payers, and hire and lead the payer accounts team in achieving the objective of securing rapid, high‑quality access for patients at launch. This role reports into the VP, Market Access.

Essential Job Duties and Functions Leading Payer Account Strategy

Understand the patient and treatment journey, and ensure all payer account strategies and initiatives reflect the priorities of the patient, community, and Edgewise

Lead payer account strategy and management (e.g., relationship building/management, business planning, pre‑ and post‑pivotal and PDUFA customer approach, business/GTN impact, pull‑through)

Partner with Market Access, HEOR, Commercial, Medical, and other cross‑functional teams to adapt the market access strategy for launch products

Bring the voice and insights of the customer into key workstreams; be an active and strategic thought‑partner to internal teams and initiatives. Understand and contribute to the development of core launch/commercial strategies

Collaborate with Commercial Operations to measure account performance and communicate situation analysis, approach, and results to internal audiences, including executives

Support the development of key market access strategies and tactics

Maintain an up‑to‑date understanding of evolving U.S. market access landscape (e.g., industry consolidation, pricing policy, access‑related regulation, patient affordability, rare disease drug coverage)

Securing Rapid, High‑Quality Access for Patients

Be the primary account lead for at least one of the “big‑3” payer organizations

Define payer account team structure and hire/motivate/retain payer account team members

Understand and help define anticipated access for sevasemten and EDG‑7500, including timing and specific criteria that determine quality of coverage

Adopt a “turn over every stone” approach to access for patient communities. Secure multiple opportunities to educate payers on Edgewise, pipeline, and key products: pre‑ and post‑Ph3 data, pre‑ and post‑PDUFA. These engagements should ideally be in‑person but virtual when appropriate

Effectively communicate the clinical and economic value story of Edgewise products to pharmacy, medical, clinical, and other payer stakeholders, independently and in collaboration with Field HEOR

Lead and represent Edgewise at market access conferences and congresses

Upon approval, accountable for securing rapid, high‑quality access by executing market access strategy

Proactively identify innovative ways to improve patient access (e.g., data, partnerships, programs)

Ensure all interactions and initiatives are professional, ethical, and compliant

Supporting Patient Access and Pull‑Through Efforts

Be a subject matter expert on market access landscape, access, and payers to internal teams

Lead efforts to bring the voice of the patient and provider community to payer audiences

Support cross‑functional efforts to improve Edgewise teams’ access literacy and effectiveness in securing coverage (e.g., Commercial, Patient Advocacy, Patient Services, Medical)

Support pull‑through efforts from Edgewise field teams, including advocating with customers to resolve access issues on behalf of patients, when compliant, appropriate, and necessary

As necessary, support center of excellence/integrated delivery network adoption of new Edgewise products, including engagement with hospital Pharmacy & Therapeutics committees and other executives

Required Education, Experience and Skills

BS/BA with at least 12+ years pharma/biotech industry experience in market access account management, with at least 2‑3 years in the rare disease environment

U.S. market access experience launching products is required, preferably with first‑in‑disease or first‑in‑class therapies

Track record of success in payer engagement pre‑ and post‑PDUFA and securing rapid, high‑quality access for rare and specialty drugs

Experience in market access and account team culture‑focused leadership

Remote role with potential of frequent travel (up to 75%) to headquarters, internal meetings, customers, and relevant conferences/meetings as necessary

Salary range: $250,000 - $300,000, title and salary commensurate with experience

Our Benefits: We are proud to offer health benefits, a discretionary bonus plan, stock option grants, a stock purchase plan, a 401(k) with match and paid time off to our team members as part of their compensation plan.

Edgewise does not accept resumes from recruitment agencies for this position. Please do not send resumes to Edgewise employees or the company location. Edgewise is not responsible for any fees related to unsolicited resumes.

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