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Director, US Value & Access

Ionis Pharmaceuticals, Inc., Carlsbad, CA, United States


Overview Headquartered in Carlsbad, California, with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis is a leader in RNA-targeted medicines with a growing pipeline in neurology, cardiology and select areas of high patient need. We pursue innovation in RNA therapies and are advancing new approaches in gene editing to provide value to patients. Ionis supports onsite, hybrid and remote work environments and values diverse individuals, skills and perspectives.

We invite you to apply to join our team and contribute to a culture that fosters scientific excellence and meaningful impact on patients in need.

Position: Director, US Value & Access Summary

The Director, Value & Access leads the development and execution of comprehensive value and market access strategies to ensure optimal patient access and commercial success across the designated therapeutic area. This role integrates cross-functional leadership and collaboration across Commercial, Medical, HEOR, and Regulatory to shape payer strategy, evidence generation, and value communication throughout the product lifecycle. The Director operates as a strategic leader with significant autonomy, influencing enterprise-level decisions.

Responsibilities

Develop and lead U.S. market access strategies aligned with brand and portfolio objectives across a 3+ year horizon.

Define value proposition and access roadmap from pre-launch through lifecycle management.

Shape and implement integrated evidence plans, in partnership with HEOR and Medical Affairs to support access and payer negotiations.

Serve as the enterprise subject matter expert on access, payer dynamics, and policy trends across the landscape and within specialty and rare disease.

Oversee development of AMCP dossiers, payer communication tools (including Pre-approval Information Exchange and Payer Value Proposition) and field access tools (including product coverage, prior authorization criteria and patient support options).

Guide economic modeling and budget impact analyses to support payer discussions.

Collaborate and partner closely with Commercial to align access strategy with brand strategy.

Engage with Government Affairs on policy implications and advocacy priorities.

Represent the organization in external advisory boards and industry forums.

Monitor payer landscape, competitive dynamics, and regulatory changes to inform strategy.

Lead, coach, and develop high-performing Market Access professionals.

Select and retain agency partners, holding full budget authority for access strategies.

Drive cross-functional alignment in matrixed environments.

Qualifications

Bachelor’s degree required; advanced degree preferred.

15+ years of experience with a Bachelor’s degree (or 10+ with advanced degree) in U.S. Market Access, Value & Access, Payer Marketing, or related roles.

Proven experience leading access strategy for product launches with a strong understanding of U.S. payer systems and reimbursement pathways.

Experience with specialty pharmaceuticals and/or rare disease preferred.

Demonstrated collaboration and leadership experience in matrixed organizations.

For more information about Ionis and to apply for this position, please visit http://www.ionis.com and reference requisition # IONIS003992. Ionis offers an excellent benefits package. For full benefits details, please visit Ionis Benefits link. The pay scale for this position is $220,000 to $260,000. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

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