Executive Director of Oncology Pharmacokinetics and Modeling (BOSTON)
Takeda Pharmaceutical Company Ltd, Boston, MA, United States
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The Oncology (ONC) Therapeutic Area Lead in DMPK&M will have strong scientific and strategic leadership to impact broad responsibilities on the pipeline, talent, and strategy. This role will supervise and lead a team of DMPK&M project representatives and Modeling & Simulation (M&S) scientists responsible for delivering on Takeda’s research pipeline in the ONC therapeutic area.
This role is responsible for oversight on the DMPK&M strategy of the ONC portfolio and ensures the execution of DMPK&M project plans, translation, and dose optimization strategies, as well as review of regulatory filings.
Key deliverables will be contributing to portfolio strategy and global business operations within DMPK&M.
Demonstrates leadership experience in guiding talented teams and is a key member of the Global DMPK&M leadership team that drives department strategy, creates a positive and effective department culture, and strengthens partnerships across the Research and Development organizations within Takeda.
Leads a team of DMPK project representatives and modeling scientists who have key scientific and strategic input to research projects to enable Takeda to meet its global research goals.
Accountable for strategic planning and scientific oversight of the discovery and development portfolio for the ONC therapeutic area.
Drives the development of organizational culture and capabilities by building strong alliances across the Research and Development organizations within Takeda.
Scientific responsibilities: Provides scientific leadership and strategic guidance on stage-appropriate questions related to DMPK&M to ensure the selection and development of clinical candidates with optimal drug development characteristics. Builds and enhances an external network to keep a pulse on scientific developments, novel strategies, partnership opportunities, and the latest competitive and regulatory landscape, particularly in relation to the ONC therapeutic areas. Oversees and participates in regulatory activities, including the review and approval of robust and fit-for-purpose submission packages in the ONC therapeutic area.
As the DMPK&M ONC Therapeutic Area Lead, this role will facilitate the alignment of DMPK&M strategy with DDU and TAU portfolio goals. Collaborate with DDU and TAU senior leaders, communicating needs, strategy, and execution plans, while consulting with DMPK leadership to ensure resources and goals are aligned. Accountable for appropriate resourcing of project support by collaborating with the Global DMPK&M leadership team. Management responsibilities: ~ Comprehensive understanding of drug discovery and development, the pharmaceutical industry, DMPK&M science.
Excellent communicator can persuasively convey both ideas and data, verbally and in writing. Embraces and demonstrates a diversity and inclusion mindset and role models these behaviors for the organization. Invests time in helping others to enhance their skills and perform at a higher level.
Cultivates a broad network of relationships throughout Takeda, with affiliates and external partners, in the industry and area of expertise. Ability to take risks implementing innovative solutions, accelerating time to market.
PhD degree in a scientific discipline with 15+ years experience, MS with 21+ years experience, or BS with 23+ years experience including at least 9 years of Industry experience in pharmaceutical DMPK and modeling Good understanding of the (NS, ONC or ONC) DDU/TAU project portfolio, disease indications, and typical DMPK&M considerations for patients Experience in managing preclinical scientists and preparation of INDs, CTDs, NDAs, and MAAs. Exceptional leadership, coaching, employee development skills. In-depth knowledge of the functional area, business strategies, and the company’s goals. A track record of sustained, significant scientific contributions in DMPK and modeling, as demonstrated by publications and presentations.
This position is currently classified as “ hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.
Scientific responsibilities: Provides scientific leadership and strategic guidance on stage-appropriate questions related to DMPK&M to ensure the selection and development of clinical candidates with optimal drug development characteristics. Builds and enhances an external network to keep a pulse on scientific developments, novel strategies, partnership opportunities, and the latest competitive and regulatory landscape, particularly in relation to the ONC therapeutic areas. Oversees and participates in regulatory activities, including the review and approval of robust and fit-for-purpose submission packages in the ONC therapeutic area.
As the DMPK&M ONC Therapeutic Area Lead, this role will facilitate the alignment of DMPK&M strategy with DDU and TAU portfolio goals. Collaborate with DDU and TAU senior leaders, communicating needs, strategy, and execution plans, while consulting with DMPK leadership to ensure resources and goals are aligned. Accountable for appropriate resourcing of project support by collaborating with the Global DMPK&M leadership team. Management responsibilities: ~ Comprehensive understanding of drug discovery and development, the pharmaceutical industry, DMPK&M science.
Excellent communicator can persuasively convey both ideas and data, verbally and in writing. Embraces and demonstrates a diversity and inclusion mindset and role models these behaviors for the organization. Invests time in helping others to enhance their skills and perform at a higher level.
Cultivates a broad network of relationships throughout Takeda, with affiliates and external partners, in the industry and area of expertise. Ability to take risks implementing innovative solutions, accelerating time to market.
PhD degree in a scientific discipline with 15+ years experience, MS with 21+ years experience, or BS with 23+ years experience including at least 9 years of Industry experience in pharmaceutical DMPK and modeling Good understanding of the (NS, ONC or ONC) DDU/TAU project portfolio, disease indications, and typical DMPK&M considerations for patients Experience in managing preclinical scientists and preparation of INDs, CTDs, NDAs, and MAAs. Exceptional leadership, coaching, employee development skills. In-depth knowledge of the functional area, business strategies, and the company’s goals. A track record of sustained, significant scientific contributions in DMPK and modeling, as demonstrated by publications and presentations.
This position is currently classified as “ hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.