Director, Global Commercial Strategy - GI

Director, Global Commercial Strategy – GI (Horsham, PA or Spring House, PA) Purpose Drive integrated commercial strategy across early discovery through late-stage GI development assets. Partner with GCSO, R&D, Medical Affairs, Market Access, Business Development, and regional teams to embed commercial input early, shape development decisions, advance launch readiness, and maximize long-term asset/portfolio value.
Key Responsibilities Early Development & Portfolio Strategy Serve as commercial lead for early-stage Compound Development Teams; embed commercial strategy from discovery through proof-of-concept.
Translate DAS roadmap into asset-level strategies (disease spaces, patient segments, value drivers, differentiation, evidence needs).
Shape TPPs, indication sequencing, competitive positioning, and go
o-go criteria.
Provide input into clinical trial design (endpoints, comparator, patient enrichment, line-of-therapy, label-enabling evidence).
Drive portfolio prioritization and evaluate external assets/combination/white-space opportunities.
Develop executive-ready recommendations for governance forums.

Late Development & Launch Preparation Translate asset strategy into launch-ready commercial plans (indication prioritization, evidence gaps, positioning, value proposition).
Lead late-stage commercial workstreams with forecasting from regional input.
Shape pre-launch planning (TPP refinement, launch sequencing, brand positioning, evidence, stakeholder engagement).
Pressure-test launch assumptions; develop recommendations for governance/investment decisions.

Qualifications Bachelor’s degree required; advanced degree preferred (MBA, PharmD, PhD, MD, or related).
10+ years progressive experience in commercial strategy/marketing/business development/market access/medical affairs/R&D strategy or related.
Demonstrated commercial strategy experience across pipeline/early/late-stage/launch assets (ideally immunology, gastroenterology, or specialty medicine).
Strong understanding of drug development, clinical trial design/endpoints, regulatory considerations, evidence generation, market access, and global commercialization.
Excellent written/verbal communication; executive-ready narratives.
Preferred Ability to shape TPPs, value propositions, positioning, and investment recommendations.
Experience leading complex global cross-functional initiatives in a matrix environment; influence senior stakeholders without direct authority.
Other Up to 10% domestic and international travel.

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