Director, Global Commercial Strategy – GI (Horsham, PA or Spring House, PA)
Purpose
Drive integrated commercial strategy across early discovery through late-stage development assets in the GI portfolio; embed commercial input early, shape development decisions, advance launch readiness, and maximize long-term asset/portfolio value.
Key Responsibilities
- Serve as commercial lead for early-stage Compound Development Teams (CDTs); embed strategy from discovery to proof-of-concept aligned to DAS roadmap and portfolio value.
- Translate DAS roadmap into asset-level strategies (disease spaces, patient segments, clinical value drivers, differentiation requirements, evidence needs).
- Shape TPPs, indication sequencing, competitive positioning, and go
o-go criteria. - Provide commercial input into clinical trial design (endpoints, comparators, enrichment, line-of-therapy, label-enabling evidence).
- Drive portfolio prioritization (unmet need, competitive intensity, differentiation, market access feasibility, revenue potential).
- Partner to evaluate external assets, combinations, and white-space opportunities.
- Develop executive-ready recommendations for governance forums.
- Translate asset strategy into launch-ready commercial plans; lead late-stage commercial workstreams and pre-launch planning (positioning, evidence generation, stakeholder engagement, milestones).
- Lead competitive strategy/differentiation; partner on scientific narrative/evidence and value/reimbursement; generate actionable insights with GCI.
Education/Qualifications
- Bachelor’s required; advanced degree preferred (MBA, PharmD, PhD, MD, or related discipline).
- 10+ years progressive experience in commercial strategy/marketing/business development/market access/medical affairs/R&D strategy or related.
- Experience across pipeline, early/late/launch assets (ideally immunology, gastroenterology, specialty medicine).
- Strong drug development, clinical trial, regulatory, evidence generation, market access, and global commercialization knowledge.
Preferred
Ability to shape TPPs/value propositions/asset positioning/investment recommendations; lead complex global cross-functional initiatives in matrix settings.
Other
Up to 10% domestic and international travel.
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