Scientific Senior Specialist, Cell Therapy
Atrium, Boston, MA, United States
Job Description
Vertex is looking for a talented individual to join our team as a scientific specialist contractor in Cell Therapy Core & process development team. In this key role, you’ll lead the development and production of high-quality media and cell therapy products, to support our Cell and Gene Therapy projects. As a senior contractor, you’ll be crucial in our process development, setting schedules, and maintaining production operations, schedules. This role will focus on process development, drug substance material generation and supervising operations for media, factors, reagents.
Our Process Development group is dynamic and fast-paced, ideal for those who excel in energetic environments. We’re seeking an expert in Stem cells Upstream processing or related fields, with a strong background in technical operations.
Key Responsibilities
Perform stem cell therapy process development and drug substance (DS) production activities, including DS/DP characterization, process investigations, and manufacturing support
Execute stem cell therapy experiments, including routine cell passaging, bioreactor-based cell expansion, and harvest, formulation operations
Design and execute experiments to optimize media components, supplements, and overall cell culture performance
Evaluate and implement new technologies to advance cell therapy development capabilities
Media & Reagent Operations Management
Oversee and execute the preparation of cell culture media, growth factors, reagents, and buffers for large-scale operations
Manage kitting activities and inventory control for critical raw materials
Develop and optimize standard operating procedures (SOPs) and protocols for media and solution preparations, ensuring high quality and compliance with cGxP standards
Troubleshoot technical issues in media preparation processes and ensure operational efficiency
Cross-Functional Collaboration
Collaborate with Analytical Development (AD) and Process Development (PD) teams to ensure seamless production operations and technical alignment, maintain request and tracking system (e.g. Smartsheet)
Support PD, AD activities through process optimization and technical troubleshooting and knowledge sharing
Qualifications
Strong knowledge and hands-on experience in media development and cell culture (stem cell culture experience preferred).
Proficiency in analytical tools (e.g., spent media analysis, omics), aseptic techniques bioreactor operations.
Excellent operational excellence, organizational, verbal, and written communication skills.
Ability to manage multiple tasks, meet deadlines, and adapt to changing priorities.
Availability for weekend work to support stem cell culture activities as needed.
Bachelors/ MS in Chemistry/ Chemical Engineering or related discipline with 4+ years of industry experience; an MS with 2+ years of industry experience
Contract Length:
12 months with the chance to extend.
Pay Range $45.00 - $55.00/hr
Shift/Hours Monday - Friday; weekend availability required
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Our Process Development group is dynamic and fast-paced, ideal for those who excel in energetic environments. We’re seeking an expert in Stem cells Upstream processing or related fields, with a strong background in technical operations.
Key Responsibilities
Perform stem cell therapy process development and drug substance (DS) production activities, including DS/DP characterization, process investigations, and manufacturing support
Execute stem cell therapy experiments, including routine cell passaging, bioreactor-based cell expansion, and harvest, formulation operations
Design and execute experiments to optimize media components, supplements, and overall cell culture performance
Evaluate and implement new technologies to advance cell therapy development capabilities
Media & Reagent Operations Management
Oversee and execute the preparation of cell culture media, growth factors, reagents, and buffers for large-scale operations
Manage kitting activities and inventory control for critical raw materials
Develop and optimize standard operating procedures (SOPs) and protocols for media and solution preparations, ensuring high quality and compliance with cGxP standards
Troubleshoot technical issues in media preparation processes and ensure operational efficiency
Cross-Functional Collaboration
Collaborate with Analytical Development (AD) and Process Development (PD) teams to ensure seamless production operations and technical alignment, maintain request and tracking system (e.g. Smartsheet)
Support PD, AD activities through process optimization and technical troubleshooting and knowledge sharing
Qualifications
Strong knowledge and hands-on experience in media development and cell culture (stem cell culture experience preferred).
Proficiency in analytical tools (e.g., spent media analysis, omics), aseptic techniques bioreactor operations.
Excellent operational excellence, organizational, verbal, and written communication skills.
Ability to manage multiple tasks, meet deadlines, and adapt to changing priorities.
Availability for weekend work to support stem cell culture activities as needed.
Bachelors/ MS in Chemistry/ Chemical Engineering or related discipline with 4+ years of industry experience; an MS with 2+ years of industry experience
Contract Length:
12 months with the chance to extend.
Pay Range $45.00 - $55.00/hr
Shift/Hours Monday - Friday; weekend availability required
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