Senior Director, Sales Operations (Oncology)

Princeton, NJ (US)

About Summit

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are the heart of our culture and essential to shaping Summit’s journey toward excellence.

Summit’s team is focused on oncology clinical studies. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

HARMONi: Phase 3 evaluating ivonescimab with chemotherapy vs placebo with chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC previously treated with a 3rd generation EGFR TKI.

HARMONi-3: Phase 3 evaluating ivonescimab with chemotherapy vs pembrolizumab with chemotherapy in first-line metastatic NSCLC.

HARMONi-7: Phase 3 evaluating ivonescimab monotherapy vs pembrolizumab monotherapy in first-line metastatic NSCLC.

HARMONi-GI3: Phase 3 evaluating ivonescimab in combination with chemotherapy vs bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s NMPA. Summit is headquartered in Miami, FL, with additional offices in California, New Jersey, the UK, and Ireland.

Overview of Role

The Senior Director of Sales Operations (Oncology) is responsible for building and leading the commercial infrastructure that supports the oncology field force and drives execution excellence. This role oversees incentive compensation, field analytics, CRM operations, territory design, reporting, and fleet. The ideal candidate has deep experience supporting oncology sales teams, strong analytical capabilities, and the ability to partner cross-functionally to maximize field performance and commercial impact for patients. The position will also develop educational content in collaboration with Marketing and Sales Training to address ongoing analytical education and tactical execution opportunities.

Role and Responsibilities

• Lead day-to-day sales operations for the oncology sales organization, ensuring high-quality support and operational readiness
• Partner with Sales, Marketing, and Market Access teams to align commercial strategy and field execution priorities
• Establish scalable processes to support new launches, new indications, and expansion of the oncology portfolio
• Partner cross-functionally to develop key performance metrics and dashboards that help the sales organization focus on performance drivers
• Lead the design, modeling, and administration of compliant incentive compensation plans, ensuring fairness, clarity, and motivation for the field force
• Coordinate data availability and Q/A process for sales reporting with cross-functional teams and vendors
• Deliver sales reports, dashboards, IC scorecards, resource allocation recommendations, and next best actions
• Manage CRM platforms (e.g., Veeva or Salesforce) including workflows, call plans, segmentation, and reporting capabilities
• Develop targeting and segmentation strategies that optimize field execution across oncology HCPs & HCOs
• Manage alignment of territories/regions to maximize field effectiveness and ensure compliance in promotional activities and IC plan equity
• Support digital engagement programs, field-triggered digital content, and omnichannel alignment with marketing ops
• Support contracting and execution of Field support tools and licenses (e.g., RxVantage, Mobile Locker, Vendormate)
• Manage field Fleet program
• Manage vendor relationships (CRM, data providers, IC consultants, analytics tools, roster management)
• Ensure compliance with legal, regulatory, and quality standards for all field operations activities
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills

• Bachelor’s degree required; MBA or advanced degree preferred
• Minimum of 12+ years Commercial / Sales Operations experience in the Pharma/Biotech industry
• Oncology experience strongly preferred
• Deep understanding of oncology market dynamics, data sources, field roles, and buying pathways
• Detailed understanding of sales processes, sales data tracking, sales force automation, incentive compensation operations, and sales force alignments
• Ability to develop and effectively coach direct reports
• Proficient in all aspects of analyzing healthcare sales data and field force activities
• Expertise in CRM platforms (Veeva/Salesforce), IC modeling, forecasting, and commercial analytics
• Excellent verbal, written and stakeholder management skills to influence and manage expectations with sales management and cross-functional teams
• Strong leadership, communication, cross-functional collaboration, and project-management skills
• Ability to excel in fast-paced, high-growth biotech environments

This is the pay for this position

Pay Transparency

$231,000 - $285,000 USD

Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may differ in other locations due to differences in the cost of labor. The total compensation package may include bonus, stock, benefits and/or other variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies for vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at to obtain prior written authorization before referring any candidates.

Summit Therapeutics Inc. is an Equal Opportunity Employer and is committed to creating and maintaining a diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

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