Portfolio Strategy and Performance Lead

Overview

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place. Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Vaccines is the only place in Pfizer where you can contribute to patients in a way like no other – you can prevent sickness and disease. This is a critical leadership position, responsible for establishing and owning implementation of a connected strategy across the pediatrics / maternal / public team, aligned with U.S. Vaccines and Pfizer Primary Care goals and performance objectives. The Senior Director will lead key strategic initiatives and facilitate performance management, and execution for Pfizer’s U.S. Pediatric, Maternal & Public Vaccines portfolio, including key assets such as Prevnar 20 Pediatric, ABRYSVO Maternal, Penbraya and Trumenba. The role is critical in shaping portfolio strategy, driving commercial readiness, and ensuring alignment across cross-functional teams to deliver on Pfizer’s mission of preventing disease and improving public health outcomes.

Role Responsibilities

• Define and execute the U.S. pediatric/maternal vaccines portfolio strategy, aligned with global objectives and U.S. market dynamics.
• Lead scenario planning and strategic roadmap development for ACIP recommendations and competitive market shifts.
• Optimize resource allocation across brands to maximize portfolio impact.
• Establish KPIs and dashboards to monitor portfolio health and identify growth opportunities.
• Partner with finance and analytics teams for accurate forecasting and performance tracking.
• Oversee aligned performance goals across channel, customer-facing and enabling teams, refreshed according to the semesterly performance review cycle.
• Establish KPIs and management for portfolio-based initiatives (e.g., adherence tactics).
• Establish response plans and mitigation strategies as relevant and operationalize through applicable cross-functional teams.
• Collaborate with marketing, medical, regulatory, access, and account management teams to ensure seamless execution of portfolio initiatives.
• Ensure commercial readiness for new indications and platform changes.
• Develop strategies to address healthcare disparities and promote equity in pediatric and maternal immunization.
• Build strong relationships with healthcare providers, payers, and organized customers to drive vaccination uptake.
• Represent Pfizer at key industry forums and advisory committees.
• Conduct periodic and ad-hoc scenario analyses to assess the impact of external and internal dynamics on vaccination strategies, market uptake, inventory dynamics and market share; inform forecasting and investment decision-making.

Qualifications

• Bachelor’s degree and 12 or more years of experience, 10 years with MBA, 7 years with PhD/equivalent
• Preference for vaccines experience and buy & bill business models, although not required
• Strong familiarity with the US marketing landscape including HCP, pharmacy, medical group/integrated delivery network and payer engagement strategies
• Demonstrated matrix leadership and ability to foster a culture of collaboration and successful delivery across cross-functional partners
• Active contributor to an environment that embraces bold, innovative ideas
• Excellent communication and organizational skills, demonstrated through impact in prior roles
• Acts as a role model for Pfizer values

Other Job Details

• Last Date to Apply for Job: March 26, 2026
• Eligible for Relocation Package: No
• Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week or more as needed.

Salary for this position ranges from $214,900.00 to $358,100.00 base pay. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a target bonus of 22.5% of base salary and eligibility to participate in our long-term incentive program. Pfizer offers comprehensive benefits including 401(k) with company matching, retirement contributions, paid vacation/holiday/personal days, parental and caregiver leave, medical/dental/vision coverage, and more. Relocation assistance may be available based on business needs and eligibility.

Sunshine Act & EEO

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws. Pfizer is committed to equal opportunity in employment and complies with applicable laws. This position requires permanent work authorization in the United States. For accessibility issues or accommodation requests, please contact

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