
Sr. Director, Health Systems Marketing
Guardant Health, California, MO, United States
Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.
Role Overview
The Sr. Director, Health Systems Marketing is the enterprise marketing leader responsible for accelerating Shield adoption and scale across National and Regional health system accounts. This role owns the multi-year health systems marketing strategy, enterprise value proposition, and executive-facing narrative that translates clinical evidence, economic value, operational feasibility, and ecosystem dynamics into system-ready programs that drive measurable commercial impact. The leader serves as the voice of the health system customer internally and operates as a core partner to field leadership, the Health Systems Program Office/KAM Excellence function, Brand Marketing, Medical Affairs, HEOR, Market Access, Policy, Analytics/CRM, and EMR Integration. Success requires executive presence, deep health systems ecosystem fluency, and the ability to lead cross-functionally to scale repeatable adoption. This role follows a hybrid work model, with occasional on-site presence at our Palo Alto headquarters, typically 1–2 times per month, as needed and aligned with leadership. Defining Success In This Role
Measurable contribution to Shield enterprise adoption and scale, including influence on pipeline progression, pilot-to-scale conversion, and sustained ordering pull-through. A clear, differentiated health systems value proposition and narrative system tailored by stakeholder persona and account archetype. A closed-loop voice-of-customer and executive engagement engine that consistently informs messaging, tools, playbooks, and evidence priorities. Tight alignment to the Health Systems operating cadence, with early identification of adoption barriers and rapid mobilization of cross-functional solutions. Integrated provider-facing and direct-to-patient pull-through messaging and resources that support sustained demand and health system workflow adoption. Full-funnel measurement and continuous optimization of health systems marketing programs and enablement. Essential Duties And Responsibilities
Own the Health Systems Marketing strategy and multi-year roadmap for Shield, aligning to enterprise goals and evolving with evidence, guidelines, quality measures, and the value-based care landscape. Build and continuously refine the enterprise value proposition and narrative architecture for Shield, integrating clinical, economic, operational, and quality/VBC alignment for C-suite, population health, quality, finance, operations, IT, and clinical leaders. Drive account-based marketing strategy for priority health systems, creating scalable programs and resources that accelerate adoption from interest to pilots to enterprise standardization. Build and run a closed-loop voice-of-customer and executive engagement engine (councils/advisory forums, structured insight capture, synthesis, and action tracking) to inform strategy, messaging, enablement, and service improvements. Operate within the Health Systems governance cadence in partnership with Field leadership and the Program Office, surfacing opportunities and barriers early and translating insights into cross-functional playbooks and adoption initiatives. Partner with Brand Marketing to align provider-facing enterprise marketing with direct-to-patient pull-through messaging and resources that support field needs, health system workflows, and sustained demand. Lead health systems sales enablement, developing executive-ready messaging, tools, decks, objection handling, competitive positioning, and reinforcement in partnership with field leadership. Partner with Medical Affairs, HEOR, Policy, Market Access, and Analytics to strengthen the economic and operational case for adoption, identify evidence gaps, and align marketing strategies to emerging data and access dynamics. Own full-funnel KPIs and measurement frameworks, using data to optimize programs and clearly quantify marketing impact on adoption and revenue outcomes. Own the health systems marketing operating budget and agency ecosystem; build and lead a high-performing team and/or agency bench to deliver priority initiatives with speed and quality. Anticipate competitive and market shifts that impact enterprise decisions and proactively shape positioning, content, and cross-functional requirements to defend and grow enterprise share. Required Qualifications
Bachelor’s degree required; 12+ years of relevant healthcare marketing experience with enterprise/B2B focus preferred. Demonstrated experience marketing to health systems/IDNs/ACOs or similar complex customers, including account-based marketing and executive messaging. Track record of building value propositions and enablement that drive measurable adoption outcomes. Preferred Qualifications
MBA or advanced degree. Diagnostics/medtech/biopharma/population health experience. Familiarity with guideline evolution, quality measures, and coverage/access dynamics. Hybrid Work Model
This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients. The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Palo Alto, CA Primary Location Base Pay Range: $259,900 - $357,400 Other US Location(s) Base Pay Range: $220,915 - $303,790 If the role is performed in Colorado, the pay range for this job is: $233,910 - $321,660 Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. All your information will be kept confidential according to EEO guidelines. To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants. Please visit our career page at: http://www.guardanthealth.com/jobs/
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The Sr. Director, Health Systems Marketing is the enterprise marketing leader responsible for accelerating Shield adoption and scale across National and Regional health system accounts. This role owns the multi-year health systems marketing strategy, enterprise value proposition, and executive-facing narrative that translates clinical evidence, economic value, operational feasibility, and ecosystem dynamics into system-ready programs that drive measurable commercial impact. The leader serves as the voice of the health system customer internally and operates as a core partner to field leadership, the Health Systems Program Office/KAM Excellence function, Brand Marketing, Medical Affairs, HEOR, Market Access, Policy, Analytics/CRM, and EMR Integration. Success requires executive presence, deep health systems ecosystem fluency, and the ability to lead cross-functionally to scale repeatable adoption. This role follows a hybrid work model, with occasional on-site presence at our Palo Alto headquarters, typically 1–2 times per month, as needed and aligned with leadership. Defining Success In This Role
Measurable contribution to Shield enterprise adoption and scale, including influence on pipeline progression, pilot-to-scale conversion, and sustained ordering pull-through. A clear, differentiated health systems value proposition and narrative system tailored by stakeholder persona and account archetype. A closed-loop voice-of-customer and executive engagement engine that consistently informs messaging, tools, playbooks, and evidence priorities. Tight alignment to the Health Systems operating cadence, with early identification of adoption barriers and rapid mobilization of cross-functional solutions. Integrated provider-facing and direct-to-patient pull-through messaging and resources that support sustained demand and health system workflow adoption. Full-funnel measurement and continuous optimization of health systems marketing programs and enablement. Essential Duties And Responsibilities
Own the Health Systems Marketing strategy and multi-year roadmap for Shield, aligning to enterprise goals and evolving with evidence, guidelines, quality measures, and the value-based care landscape. Build and continuously refine the enterprise value proposition and narrative architecture for Shield, integrating clinical, economic, operational, and quality/VBC alignment for C-suite, population health, quality, finance, operations, IT, and clinical leaders. Drive account-based marketing strategy for priority health systems, creating scalable programs and resources that accelerate adoption from interest to pilots to enterprise standardization. Build and run a closed-loop voice-of-customer and executive engagement engine (councils/advisory forums, structured insight capture, synthesis, and action tracking) to inform strategy, messaging, enablement, and service improvements. Operate within the Health Systems governance cadence in partnership with Field leadership and the Program Office, surfacing opportunities and barriers early and translating insights into cross-functional playbooks and adoption initiatives. Partner with Brand Marketing to align provider-facing enterprise marketing with direct-to-patient pull-through messaging and resources that support field needs, health system workflows, and sustained demand. Lead health systems sales enablement, developing executive-ready messaging, tools, decks, objection handling, competitive positioning, and reinforcement in partnership with field leadership. Partner with Medical Affairs, HEOR, Policy, Market Access, and Analytics to strengthen the economic and operational case for adoption, identify evidence gaps, and align marketing strategies to emerging data and access dynamics. Own full-funnel KPIs and measurement frameworks, using data to optimize programs and clearly quantify marketing impact on adoption and revenue outcomes. Own the health systems marketing operating budget and agency ecosystem; build and lead a high-performing team and/or agency bench to deliver priority initiatives with speed and quality. Anticipate competitive and market shifts that impact enterprise decisions and proactively shape positioning, content, and cross-functional requirements to defend and grow enterprise share. Required Qualifications
Bachelor’s degree required; 12+ years of relevant healthcare marketing experience with enterprise/B2B focus preferred. Demonstrated experience marketing to health systems/IDNs/ACOs or similar complex customers, including account-based marketing and executive messaging. Track record of building value propositions and enablement that drive measurable adoption outcomes. Preferred Qualifications
MBA or advanced degree. Diagnostics/medtech/biopharma/population health experience. Familiarity with guideline evolution, quality measures, and coverage/access dynamics. Hybrid Work Model
This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients. The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Palo Alto, CA Primary Location Base Pay Range: $259,900 - $357,400 Other US Location(s) Base Pay Range: $220,915 - $303,790 If the role is performed in Colorado, the pay range for this job is: $233,910 - $321,660 Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. All your information will be kept confidential according to EEO guidelines. To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants. Please visit our career page at: http://www.guardanthealth.com/jobs/
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