Senior Director - Therapy Area Modelling Lead, Pharma
GSK, Collegeville, PA, United States
Senior Director – Therapy Area Modelling Lead, Pharma
Locations: UK – London – New Oxford Street, USA – Pennsylvania – Upper Providence.
Reports to: Head, Modelling & Evidence Synthesis.
Join GSK's Chief Patient Organisation (CPO) and be part of a global organisation that drives innovation, scientific excellence, and patient‑centred solutions. At GSK, we are committed to improving lives by ensuring the safe and effective use of our medicines and vaccines, bridging critical scientific insights with impactful healthcare strategies.
In this role you will lead a team that applies innovative modelling and evidence‑generation approaches to shape reimbursement and access strategy across therapeutic areas. You will partner with cross‑functional teams, vendors, and external experts to develop transparent, robust cost‑effectiveness, public‑health impact, budget‑impact models as well as models for early decision‑making. We value clear scientific thinking, strong communication and practical problem solving.
The role is hybrid. Expect regular time in the office (typically 2‑3 days per week) with flexibility for remote work when appropriate.
Key Responsibilities
Lead, build and mentor an economic modelling team across therapy areas within pharma.
Lead development of global models for medicines preparing for launch/HTA reimbursement applications, in alignment with medicine strategy.
Drive innovation through engagement with external experts, decision‑makers, HTA agencies, methodology and policy forums.
Facilitate alignment and partnership to enable more effective interactions within the complex stakeholder matrix (e.g., clinical, commercial, market access, medical affairs priority market LOCs).
Deliver materials to inform internal governance decision‑making (e.g., Medical Review Board).
Lead early economic models to inform clinical development, trial design and evidence plans.
Act as an in‑house expert for product teams on modelling, HTA requirements and payer evidence needs.
Represent the modelling function in scientific advice meetings, cross‑functional asset teams and external engagements.
Basic Qualifications & Skills
Advanced degree in a relevant health discipline (e.g., pharmacy, medicines, health outcomes research, health economics, economics).
Significant experience leading development of economic models and outcomes/health economics research in industry, research organisations or academia.
Proven experience contributing to HTA submissions or reimbursement dossiers.
Evidence of leading partnerships with commercial, market access and R&D functions.
Technical skills with modelling software and programming (e.g., R, Excel, decision‑analytic modelling tools).
Experience managing vendor relationships and assuring quality of outsourced deliverables.
Excellent written and verbal communication skills to explain models and results to technical and non‑technical audiences and to influence stakeholders.
Demonstrated success leading cross‑functional teams and delivering complex projects on time.
Preferred Qualifications & Skills
PhD in a relevant quantitative/health discipline.
Track record of peer‑reviewed publications as lead or first author on cost‑effectiveness or methods research.
Considerable experience with cost‑effectiveness modelling, budget‑impact modelling and local adaptations across major markets in specialty and oncology therapy areas.
Familiarity with real‑world evidence sources and their use in model inputs.
Prior experience in a global pharmaceutical or biotech/CRO company, with exposure to multiple HTA systems.
What Success Looks Like You will lead a highly‑functioning modelling team across therapy areas, deliver high‑quality, transparent economic models on time and budget, enable better decisions across development and for external decision‑makers such as HTA/reimbursement bodies, and build trusted relationships with internal partners and external experts.
Closing Date for Applications: 21st April 2026 (EOD).
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under federal, state or local law.
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Reports to: Head, Modelling & Evidence Synthesis.
Join GSK's Chief Patient Organisation (CPO) and be part of a global organisation that drives innovation, scientific excellence, and patient‑centred solutions. At GSK, we are committed to improving lives by ensuring the safe and effective use of our medicines and vaccines, bridging critical scientific insights with impactful healthcare strategies.
In this role you will lead a team that applies innovative modelling and evidence‑generation approaches to shape reimbursement and access strategy across therapeutic areas. You will partner with cross‑functional teams, vendors, and external experts to develop transparent, robust cost‑effectiveness, public‑health impact, budget‑impact models as well as models for early decision‑making. We value clear scientific thinking, strong communication and practical problem solving.
The role is hybrid. Expect regular time in the office (typically 2‑3 days per week) with flexibility for remote work when appropriate.
Key Responsibilities
Lead, build and mentor an economic modelling team across therapy areas within pharma.
Lead development of global models for medicines preparing for launch/HTA reimbursement applications, in alignment with medicine strategy.
Drive innovation through engagement with external experts, decision‑makers, HTA agencies, methodology and policy forums.
Facilitate alignment and partnership to enable more effective interactions within the complex stakeholder matrix (e.g., clinical, commercial, market access, medical affairs priority market LOCs).
Deliver materials to inform internal governance decision‑making (e.g., Medical Review Board).
Lead early economic models to inform clinical development, trial design and evidence plans.
Act as an in‑house expert for product teams on modelling, HTA requirements and payer evidence needs.
Represent the modelling function in scientific advice meetings, cross‑functional asset teams and external engagements.
Basic Qualifications & Skills
Advanced degree in a relevant health discipline (e.g., pharmacy, medicines, health outcomes research, health economics, economics).
Significant experience leading development of economic models and outcomes/health economics research in industry, research organisations or academia.
Proven experience contributing to HTA submissions or reimbursement dossiers.
Evidence of leading partnerships with commercial, market access and R&D functions.
Technical skills with modelling software and programming (e.g., R, Excel, decision‑analytic modelling tools).
Experience managing vendor relationships and assuring quality of outsourced deliverables.
Excellent written and verbal communication skills to explain models and results to technical and non‑technical audiences and to influence stakeholders.
Demonstrated success leading cross‑functional teams and delivering complex projects on time.
Preferred Qualifications & Skills
PhD in a relevant quantitative/health discipline.
Track record of peer‑reviewed publications as lead or first author on cost‑effectiveness or methods research.
Considerable experience with cost‑effectiveness modelling, budget‑impact modelling and local adaptations across major markets in specialty and oncology therapy areas.
Familiarity with real‑world evidence sources and their use in model inputs.
Prior experience in a global pharmaceutical or biotech/CRO company, with exposure to multiple HTA systems.
What Success Looks Like You will lead a highly‑functioning modelling team across therapy areas, deliver high‑quality, transparent economic models on time and budget, enable better decisions across development and for external decision‑makers such as HTA/reimbursement bodies, and build trusted relationships with internal partners and external experts.
Closing Date for Applications: 21st April 2026 (EOD).
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under federal, state or local law.
#J-18808-Ljbffr