Executive Director Global Project Leader, Oncology R&D

Executive Director Global Product Lead, Oncology R&D

At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We continuously forge partnerships that help pursue world‑class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

Overview

Join us at AstraZeneca as an Executive Director Global Product Lead (GPL) in Oncology R&D. This role offers the opportunity to lead and be accountable for multiple global cross‑functional early global product teams across diverse biological mechanisms. As the "CEO" of the asset, you will have the chance to make a big impact and be part of the team that aims to eliminate cancer as a cause of death.

Major Duties and Responsibilities

• Leads global product teams from preclinical candidate selection through proof of concept leading to Phase III.
• Investment decisions. If appropriate, GPLs may have the opportunity to continue to lead assets through late development/registration.
• Single point of accountability for the strategy, budget, timeline and execution of a portfolio of pre‑clinical and clinical stage therapeutic candidates.
• Create integrated product development plans which are aligned with business objectives and are differentiated from competitor products.
• Leads and communicates the project development strategy at governance meetings to secure funding and endorsement of the strategy.
• Leads the global project team to effectively manage, mitigate and communicate risk. Responsible for monitoring emerging data and pivot when deemed necessary.
• Responsible for maintaining a high degree of team effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross‑functional team members.
• Maintains relationships with external investigators to ensure projects are consistent with evolving clinical practices.

Qualifications

• Education: Graduate degree such as a PhD, PharmD or an MD/PhD is required.
• 10+ years of experience leading oncology drug development.

Required Experience

• Demonstrated success in developing oncology agents.
• Industry experience in drug development including experience in early phase non‑clinical and/or clinical drug development and regulatory knowledge.
• Strong knowledge and understanding of the Oncology therapeutic area with experience in diverse biological mechanisms.
• Broad understanding of the evolving clinical landscape in oncology.
• Demonstrated experience leading and motivating teams in a highly matrixed environment.
• Proven record of cultivating and managing internal and external cross‑functional collaborations.
• Demonstrated success in influencing colleagues and senior leaders in various departments.
• Must demonstrate high integrity.

Desired Skills

• Experience in the development of biologics is highly desirable.
• ADC/IO/Radio Conjugates (T cell engagers, immune redirecting agents, etc) development experience is highly desirable.
• Due diligence experience as GPLs often are required to participate in business development.

Salary & Benefits

The annual base pay for this position ranges from $246,069.60 – $369,104.40. Hourly and salaried non‑exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience. In addition, our positions offer a short‑term incentive bonus opportunity; eligibility to participate in our equity‑based long‑term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered include a qualified retirement program (401(k) plan); paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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