Intern, Pharmaceutical Engineering, Drug Product, PDM
Revolution Medicines, San Francisco, CA, United States
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS‑addicted cancers. The company’s R&D pipeline focuses on RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins, including daraxonrasib (RMC‑6236), elironrasib (RMC‑6291), zoldonrasib (RMC‑9805), and RMC‑5127. As a new member of the Revolution Medicines team, you will join other outstanding professionals dedicated to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity Playing an important role as engineering support within the Drug Product team and working closely with Scientists and Process Engineers, you will support clinical‑stage and late‑stage process developments as well as preparation for Process Performance Qualification of Revolution Medicines’ compounds.
Work closely with Scientists and Process Engineers within the Drug Product group to support the transition of drug product manufacturing from clinical stage development through late stage development and Process Performance Qualification (PPQ).
Support formulation and process development and optimization studies conducted according to the principles of Quality by Design (QbD), using tools such as OFAT (one factor at a time) experiments and DOE (Design of Experiments).
Review protocols, manufacturing batch records, and development, campaign, and technical reports for clinical‑stage and late‑stage manufacturing.
Analyze data and perform statistical analysis to support process development and optimization, process capability, and process range justification.
Build and maintain databases to manage and track experimental data and results for multiple programs.
Conduct literature reviews and stay updated on the latest advancements in drug product development and manufacturing.
Required Skills, Experience and Education
Working towards a BS, MS, or Ph.D. in Chemical Engineering, Pharmaceutical Sciences, or a related discipline.
Strong problem‑solving skills with sound, technically driven decision‑making ability.
Effective written and verbal communication skills and interpersonal skills.
Ability to review and interpret technical documents and protocols.
Strong organizational skills and attention to detail.
Ability to work collaboratively in a team environment.
Preferred Skills
Familiarity with regulatory requirements and guidelines in the pharmaceutical industry.
Knowledge of Quality by Design (QbD) principles and tools such as OFAT and DOE.
Proficiency in statistical analysis software (JMP).
Base Pay Salary Range: $67,000 – $81,000 USD.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
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The Opportunity Playing an important role as engineering support within the Drug Product team and working closely with Scientists and Process Engineers, you will support clinical‑stage and late‑stage process developments as well as preparation for Process Performance Qualification of Revolution Medicines’ compounds.
Work closely with Scientists and Process Engineers within the Drug Product group to support the transition of drug product manufacturing from clinical stage development through late stage development and Process Performance Qualification (PPQ).
Support formulation and process development and optimization studies conducted according to the principles of Quality by Design (QbD), using tools such as OFAT (one factor at a time) experiments and DOE (Design of Experiments).
Review protocols, manufacturing batch records, and development, campaign, and technical reports for clinical‑stage and late‑stage manufacturing.
Analyze data and perform statistical analysis to support process development and optimization, process capability, and process range justification.
Build and maintain databases to manage and track experimental data and results for multiple programs.
Conduct literature reviews and stay updated on the latest advancements in drug product development and manufacturing.
Required Skills, Experience and Education
Working towards a BS, MS, or Ph.D. in Chemical Engineering, Pharmaceutical Sciences, or a related discipline.
Strong problem‑solving skills with sound, technically driven decision‑making ability.
Effective written and verbal communication skills and interpersonal skills.
Ability to review and interpret technical documents and protocols.
Strong organizational skills and attention to detail.
Ability to work collaboratively in a team environment.
Preferred Skills
Familiarity with regulatory requirements and guidelines in the pharmaceutical industry.
Knowledge of Quality by Design (QbD) principles and tools such as OFAT and DOE.
Proficiency in statistical analysis software (JMP).
Base Pay Salary Range: $67,000 – $81,000 USD.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
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