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Executive Director, Head of US Bioscience, Small Molecules, Oncology Targeted Di

AstraZeneca, Waltham, MA, United States


Do you have a strategic mindset, analytical rigor, and visionary people leadership that enables you to deliver positive outcomes on high-impact projects? If you are looking to demonstrate those skills to help lead teams that shape our future oncology strategy, portfolio and decision making, we are keen to hear from you.

About AstraZeneca

At AstraZeneca, we’re building a new kind of organization to reset expectations of what a bio‑pharmaceutical company can be. We’re opening innovative ways of working, pioneering ground‑breaking methods, and bringing cross‑functional teams together. Early Oncology focuses on attacking cancer from multiple angles through innovative modalities, realizing the potential of combinations and building treatment regimens with depth, durability and precision. This senior leadership position within the Oncology Targeted Discovery Department will be accountable for the generation of bioscience data packages to support candidate drug selection and clinical positioning of assets, including prioritization of cross‑portfolio combinations.

Key Accountabilities Include

  • Providing strategic leadership and direction for the Bioscience function and partnering with the Oncology Targeted Discovery senior leadership team in the vision and execution of the small molecule bioscience strategy.
  • Evolving the capabilities and fostering a collaborative and high‑performing culture, ensuring resources are used appropriately to satisfy current and anticipated needs of the organization, and that the function drives performance and delivers business value.
  • Driving portfolio prioritization, staying abreast of the latest external developments and innovations and being able to identify future strategic opportunities.
  • Collaborating cross‑functionally with colleagues across the discovery, translational and clinical organizations.

Education, Qualifications, Skills And Experience

  • PhD in Biological science discipline.
  • Minimum of 10 years’ experience in biotechnology or pharmaceutical industry with deep drug discovery experience and ability to manage cross‑functional stakeholders.
  • Proven track record of delivering portfolio success in both pre‑clinical and clinical phase. Experience of driving innovation and delivering strategic / operational change across the business.
  • Oversight of in vivo pharmacology with awareness of local regulations.
  • Proven leadership experience promoting, motivating and empowering others to accomplish individual, team and organizational objectives. Effective interpersonal and relationship management skills with consultative approach and ability to interact and build trust.
  • Strong leadership and communication skills – ability to convey scientifically complex data and concepts in a simple, straightforward manner.
  • Ability to influence strategically and persuade tactfully, to obtain desired outcomes while maintaining effective, positive organizational relationships.
  • Expert reputation within the business and externally across the industry.

Benefits and Compensation

The annual base pay for this position ranges from $281,872.80 - $422,809.20. Hourly and salaried non‑exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience. In addition, our positions offer a short‑term incentive bonus opportunity; eligibility to participate in our equity‑based long‑term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered include a qualified retirement program (401(k) plan); paid vacation and holidays; paid leaves; and health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, the employee will be in an “at‑will” position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Equal Employment Opportunity

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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