Medicinal Chemist
Inductive Bio, San Francisco, CA, United States
Medicinal Chemist
– We are seeking an accomplished medicinal chemist to play a key role in building an AI‑forward drug discovery platform that impacts all stages of the Design‑Make‑Test‑Analyze cycle and deploy that platform to dozens of programs across the industry. This role will report directly to our Head of Medicinal Chemistry.
What you’ll do:
Be an embedded expert, supporting a variety of partner drug discovery programs from lead generation through development candidate nomination across diverse small molecule modalities.
Alongside outstanding computational chemists, DMPK, and machine learning colleagues, bring Inductive’s tools and your medchem knowledge to our work as consultants on partners’ projects.
Help deliver value to partners through Inductive’s experimental offerings, where we combine drug discovery experience, predictive models, and AI workflows with our chemistry and assay CRO partners to answer hypotheses effectively.
Build an AI‑native drug discovery platform that will speed drugs to the clinic. Help make your ideas about how to improve the DMTA cycle a reality, as we flesh out Indy (our AI medicinal chemistry agent) and build assay and synthesis workflows that get to high-quality answers more quickly.
Represent Inductive’s mission and build connections in the field, meeting with current and potential partners, gathering feedback about what drug discovery teams need, attending conferences and meetings, giving presentations, and authoring blog posts and publications.
Who you are:
An ideal candidate is a creative and accomplished medicinal chemist with a synthetic organic chemistry background who has played a meaningful role in advancing compounds to the development candidate stage. You are excited about working with partners to progress their programs, and you want to build the next generation of tools for drug discovery.
You have direct experience at all stages of drug discovery projects, and can point to go
o‑go judgement calls you’ve made in lead generation and lead optimization.
You’ve used different approaches to evaluate compound quality, from LLE to dose prediction, and appreciate the importance of contextualizing results in terms of their expected profile in humans.
The more modalities you’ve worked with, the better, from reversible and covalent to heterobifunctionals and peptides.
Along with designing compounds and analyzing data, you have years of experience in chemical synthesis with CROs. You look for convergent routes and late‑stage intermediates when thinking about synthetic strategy.
You communicate effectively and proactively, seek feedback, handle proprietary information with discretion, embrace transparency, and treat others with respect.
Experience with predictive models and automation is a plus! (e.g., FEP, predictive ADME, AI retrosynthesis, direct to biology)
Working at Inductive We offer competitive salary and equity‑based compensation; comprehensive healthcare benefits (including dental and vision); and the opportunity to grow along with a rapidly scaling company. We value a balanced life beyond work and strive to create an environment where employees can thrive both personally and professionally.
#J-18808-Ljbffr
– We are seeking an accomplished medicinal chemist to play a key role in building an AI‑forward drug discovery platform that impacts all stages of the Design‑Make‑Test‑Analyze cycle and deploy that platform to dozens of programs across the industry. This role will report directly to our Head of Medicinal Chemistry.
What you’ll do:
Be an embedded expert, supporting a variety of partner drug discovery programs from lead generation through development candidate nomination across diverse small molecule modalities.
Alongside outstanding computational chemists, DMPK, and machine learning colleagues, bring Inductive’s tools and your medchem knowledge to our work as consultants on partners’ projects.
Help deliver value to partners through Inductive’s experimental offerings, where we combine drug discovery experience, predictive models, and AI workflows with our chemistry and assay CRO partners to answer hypotheses effectively.
Build an AI‑native drug discovery platform that will speed drugs to the clinic. Help make your ideas about how to improve the DMTA cycle a reality, as we flesh out Indy (our AI medicinal chemistry agent) and build assay and synthesis workflows that get to high-quality answers more quickly.
Represent Inductive’s mission and build connections in the field, meeting with current and potential partners, gathering feedback about what drug discovery teams need, attending conferences and meetings, giving presentations, and authoring blog posts and publications.
Who you are:
An ideal candidate is a creative and accomplished medicinal chemist with a synthetic organic chemistry background who has played a meaningful role in advancing compounds to the development candidate stage. You are excited about working with partners to progress their programs, and you want to build the next generation of tools for drug discovery.
You have direct experience at all stages of drug discovery projects, and can point to go
o‑go judgement calls you’ve made in lead generation and lead optimization.
You’ve used different approaches to evaluate compound quality, from LLE to dose prediction, and appreciate the importance of contextualizing results in terms of their expected profile in humans.
The more modalities you’ve worked with, the better, from reversible and covalent to heterobifunctionals and peptides.
Along with designing compounds and analyzing data, you have years of experience in chemical synthesis with CROs. You look for convergent routes and late‑stage intermediates when thinking about synthetic strategy.
You communicate effectively and proactively, seek feedback, handle proprietary information with discretion, embrace transparency, and treat others with respect.
Experience with predictive models and automation is a plus! (e.g., FEP, predictive ADME, AI retrosynthesis, direct to biology)
Working at Inductive We offer competitive salary and equity‑based compensation; comprehensive healthcare benefits (including dental and vision); and the opportunity to grow along with a rapidly scaling company. We value a balanced life beyond work and strive to create an environment where employees can thrive both personally and professionally.
#J-18808-Ljbffr