Sr. Scientist/Assistant Director Analytical Development & Quality Control (ADQC)
Ionis Brand, Carlsbad, CA, United States
Sr. Scientist/Assistant Director Analytical Development & Quality Control (ADQC)
Job Category:
Manufacturing & Operations - Ionis
Requisition Number:
IONIS003870
Posted : April 23, 2026 Full-Time
Summary Seeking an experienced analytical chemist to join our Analytical Development & Quality Control (ADQC) group at the Sr. Research Associate, Senior Scientist or Assistant Director level (depending on experience). The ideal candidate will be familiar with a broad range of analytical chemistry techniques, possess a strong work ethic and strong technical background, demonstrate excellent oral and written communication skills, and have experience working in a GMP environment. The successful candidate will be able to perform the following responsibilities with a high degree of independence and attention to detail.
Responsibilities
Manage the analytical activities for oligonucleotide therapeutic development projects
Coordinate and execute testing of drug substance intermediate, drug substance, and drug product samples for release and stability studies
Manage outsourced analytical activities at external contract labs
Conduct analytical investigations
Develop and optimize analytical methods
Develop drug substance specifications ensuring efficient integration across Chemistry, Manufacturing, and Controls (CMC) and other relevant disciplines such as Clinical and Toxicology
Design and execute method validation and method transfer protocols
Author scientific reports and portions of the CMC section of regulatory filings
Present at internal and cross-functional scientific meetings
Requirements
BS or MS with at least 5 years (Sr. Research Associate) or 8 years (Assistant Director) of industry experience in Analytical Chemistry or related discipline
Ph.D. with at least 2 years (Sr. Scientist) or 8 years (Assistant Director) of industry experience in Analytical Chemistry or a related discipline
Skilled in operating LC-MS, HPLC, and GC for the analysis of drug substance and drug product samples
Good understanding of the drug development process
Practical knowledge of GMP requirements, with hands-on GMP experience preferred
Good understanding of ICH and FDA method validation guidelines, including phase-appropriate strategies
Ability to problem solve, manage priorities and maintain aggressive timelines for multiple projects
Ability to work productively and independently within a team or matrix environment
Excellent written and verbal communication skills
The pay scale for this position is $89,768 to $167,757
Assistant Director (non-Ph. D. track) is $89,768 to $126,913
Sr. Scientist – Principal Scientist/Assistant Director (Ph.D track) is $111,850-$167,757
NO PHONE CALLS PLEASE. PRINCIPALS ONLY.
Ionis offers an excellent benefits package! Follow this link for more details:
Ionis Benefits
Full Benefits Link:
https://ionis.com/careers#:~:text=Highly%20competitive%20benefits
Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Equal Opportunity Employer This employer is required to notify all applicants of their rights pursuant to federal employment laws.For further information, please review the Know Your Rights notice from the Department of Labor.
#J-18808-Ljbffr
Manufacturing & Operations - Ionis
Requisition Number:
IONIS003870
Posted : April 23, 2026 Full-Time
Summary Seeking an experienced analytical chemist to join our Analytical Development & Quality Control (ADQC) group at the Sr. Research Associate, Senior Scientist or Assistant Director level (depending on experience). The ideal candidate will be familiar with a broad range of analytical chemistry techniques, possess a strong work ethic and strong technical background, demonstrate excellent oral and written communication skills, and have experience working in a GMP environment. The successful candidate will be able to perform the following responsibilities with a high degree of independence and attention to detail.
Responsibilities
Manage the analytical activities for oligonucleotide therapeutic development projects
Coordinate and execute testing of drug substance intermediate, drug substance, and drug product samples for release and stability studies
Manage outsourced analytical activities at external contract labs
Conduct analytical investigations
Develop and optimize analytical methods
Develop drug substance specifications ensuring efficient integration across Chemistry, Manufacturing, and Controls (CMC) and other relevant disciplines such as Clinical and Toxicology
Design and execute method validation and method transfer protocols
Author scientific reports and portions of the CMC section of regulatory filings
Present at internal and cross-functional scientific meetings
Requirements
BS or MS with at least 5 years (Sr. Research Associate) or 8 years (Assistant Director) of industry experience in Analytical Chemistry or related discipline
Ph.D. with at least 2 years (Sr. Scientist) or 8 years (Assistant Director) of industry experience in Analytical Chemistry or a related discipline
Skilled in operating LC-MS, HPLC, and GC for the analysis of drug substance and drug product samples
Good understanding of the drug development process
Practical knowledge of GMP requirements, with hands-on GMP experience preferred
Good understanding of ICH and FDA method validation guidelines, including phase-appropriate strategies
Ability to problem solve, manage priorities and maintain aggressive timelines for multiple projects
Ability to work productively and independently within a team or matrix environment
Excellent written and verbal communication skills
The pay scale for this position is $89,768 to $167,757
Assistant Director (non-Ph. D. track) is $89,768 to $126,913
Sr. Scientist – Principal Scientist/Assistant Director (Ph.D track) is $111,850-$167,757
NO PHONE CALLS PLEASE. PRINCIPALS ONLY.
Ionis offers an excellent benefits package! Follow this link for more details:
Ionis Benefits
Full Benefits Link:
https://ionis.com/careers#:~:text=Highly%20competitive%20benefits
Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Equal Opportunity Employer This employer is required to notify all applicants of their rights pursuant to federal employment laws.For further information, please review the Know Your Rights notice from the Department of Labor.
#J-18808-Ljbffr