Analytical Chemist
Eli Lilly and Company, Indianapolis, IN, United States
Job Summary
Synthetic Molecule Design and Development has an exciting opportunity for an analytical chemist to join our development group. In this hands‑on laboratory role (>70% bench work) you will develop analytical methods and characterize chemical processes to advance drug candidates from early development through manufacturing readiness.
Position Responsibilities
Develop and optimize analytical methods to accurately measure purity, potency, and other critical quality attributes of small molecule drug substances and synthetic intermediates.
Select and implement appropriate analytical techniques (HPLC, GC, NMR, MS) to support chemical process development—generating data that elucidates reaction mechanisms, characterizes kinetic behavior, and identifies process‑related impurities.
Assess stability of development materials under stressed conditions to evaluate potential degradation using chromatographic techniques.
Collaborate with synthetic chemists and process engineers to ensure analytical methods are suitable for guiding development activities and can be successfully transferred to GMP laboratories for routine testing and manufacturing support.
Perform laboratory activities with a strong emphasis on safety and technical rigor, while adhering to local policies and procedures.
Apply new scientific concepts, exhibit strong problem‑solving skills, and be self‑motivated to contribute across multiple projects.
Demonstrate strong written and verbal communication skills to represent both the technical aspects and business‑related implications of your work.
Basic Qualifications
Bachelor or Master of Science degree in Analytical Chemistry, Biochemistry, Chemistry, or a related field.
Experience with chromatographic (LC, GC, IC) method development or validation in a pharmaceutical, chemical, or regulated industry setting.
Qualified applicants must be authorized to work in the United States on a full‑time basis. Lilly will not provide support for or sponsor work authorization or visas for this role.
Additional Skills / Preferences
Working knowledge of mass spectrometry (LC‑MS, GC‑MS) and NMR spectroscopy.
Familiarity with chemical process development, synthetic organic chemistry, and rationales for establishing material specifications and testing plans.
Experience troubleshooting and maintaining analytical instrumentation.
Demonstration of scientific leadership and the ability to influence others.
Ability to balance multiple responsibilities, prioritize activities, and navigate ambiguity.
Additional Information
Travel: 0 to 10%
Position Local: Onsite Monday through Friday, Indianapolis, IN; Lilly Technology Center‑North (LTC‑N)
Lilly is an EEO/Affirmative Action Employer and does not discriminate based on race, gender, protected veteran status, disability, or any other legally protected status.
Compensation and Benefits
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $65,250 - $169,400. Full‑time employees will be eligible for a company bonus and a comprehensive benefit program, including 401(k), pension, medical, dental, vision, prescription drug benefits, flexible benefits, life insurance, and various leave of absence and wellness benefits.
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Synthetic Molecule Design and Development has an exciting opportunity for an analytical chemist to join our development group. In this hands‑on laboratory role (>70% bench work) you will develop analytical methods and characterize chemical processes to advance drug candidates from early development through manufacturing readiness.
Position Responsibilities
Develop and optimize analytical methods to accurately measure purity, potency, and other critical quality attributes of small molecule drug substances and synthetic intermediates.
Select and implement appropriate analytical techniques (HPLC, GC, NMR, MS) to support chemical process development—generating data that elucidates reaction mechanisms, characterizes kinetic behavior, and identifies process‑related impurities.
Assess stability of development materials under stressed conditions to evaluate potential degradation using chromatographic techniques.
Collaborate with synthetic chemists and process engineers to ensure analytical methods are suitable for guiding development activities and can be successfully transferred to GMP laboratories for routine testing and manufacturing support.
Perform laboratory activities with a strong emphasis on safety and technical rigor, while adhering to local policies and procedures.
Apply new scientific concepts, exhibit strong problem‑solving skills, and be self‑motivated to contribute across multiple projects.
Demonstrate strong written and verbal communication skills to represent both the technical aspects and business‑related implications of your work.
Basic Qualifications
Bachelor or Master of Science degree in Analytical Chemistry, Biochemistry, Chemistry, or a related field.
Experience with chromatographic (LC, GC, IC) method development or validation in a pharmaceutical, chemical, or regulated industry setting.
Qualified applicants must be authorized to work in the United States on a full‑time basis. Lilly will not provide support for or sponsor work authorization or visas for this role.
Additional Skills / Preferences
Working knowledge of mass spectrometry (LC‑MS, GC‑MS) and NMR spectroscopy.
Familiarity with chemical process development, synthetic organic chemistry, and rationales for establishing material specifications and testing plans.
Experience troubleshooting and maintaining analytical instrumentation.
Demonstration of scientific leadership and the ability to influence others.
Ability to balance multiple responsibilities, prioritize activities, and navigate ambiguity.
Additional Information
Travel: 0 to 10%
Position Local: Onsite Monday through Friday, Indianapolis, IN; Lilly Technology Center‑North (LTC‑N)
Lilly is an EEO/Affirmative Action Employer and does not discriminate based on race, gender, protected veteran status, disability, or any other legally protected status.
Compensation and Benefits
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $65,250 - $169,400. Full‑time employees will be eligible for a company bonus and a comprehensive benefit program, including 401(k), pension, medical, dental, vision, prescription drug benefits, flexible benefits, life insurance, and various leave of absence and wellness benefits.
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