Postdoctoral Research Associate – Heinzen Lab
Inside Higher Ed, Chapel Hill, NC, United States
Position Summary
The Heinzen laboratory in the Division of Pharmacotherapy and Experimental Therapeutics at the Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, is seeking postdoctoral researchers to investigate the genetic and genomic bases of epilepsy. The position focuses on brain‑tissue specific genetic variants that mediate seizures and aims to identify novel treatment approaches in epilepsy.
The successful candidate will work in a highly interdisciplinary environment, collaborating across computational biology, genetics, and laboratory science. The goal is to develop specialized skill sets that support independent research careers.
Responsibilities
Optimize and implement cutting‑edge genomic analyses, including long‑read sequencing, whole‑genome sequencing, single‑cell sequencing, and chromatin conformation capture techniques, to detect somatic and germline genetic variants in brain tissue specimens associated with epilepsy.
Develop novel approaches for analyzing the genomic data generated and facilitate downstream functional studies.
Potentially functionally characterize epilepsy‑associated variants in vitro using cellular models, depending on expertise and research interests.
Partner with faculty and collaborators to advance the laboratory’s research agenda and support group goals.
Publish findings in peer‑reviewed journals and present results at national and international conferences.
Minimum Education and Experience Requirements
Ph.D. in human genetics, bioinformatics, computational biology, or a closely related field.
Demonstrated publication record that evidences research productivity and independent inquiry.
Required Qualifications, Competencies, and Experience
Excellent communication, organizational, and written communication skills.
Strong analytical and problem‑solving abilities with a drive for innovative research.
Willingness and aptitude to work collaboratively in a team‑science environment.
Ability to work independently and manage multiple projects within defined deadlines.
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The Heinzen laboratory in the Division of Pharmacotherapy and Experimental Therapeutics at the Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, is seeking postdoctoral researchers to investigate the genetic and genomic bases of epilepsy. The position focuses on brain‑tissue specific genetic variants that mediate seizures and aims to identify novel treatment approaches in epilepsy.
The successful candidate will work in a highly interdisciplinary environment, collaborating across computational biology, genetics, and laboratory science. The goal is to develop specialized skill sets that support independent research careers.
Responsibilities
Optimize and implement cutting‑edge genomic analyses, including long‑read sequencing, whole‑genome sequencing, single‑cell sequencing, and chromatin conformation capture techniques, to detect somatic and germline genetic variants in brain tissue specimens associated with epilepsy.
Develop novel approaches for analyzing the genomic data generated and facilitate downstream functional studies.
Potentially functionally characterize epilepsy‑associated variants in vitro using cellular models, depending on expertise and research interests.
Partner with faculty and collaborators to advance the laboratory’s research agenda and support group goals.
Publish findings in peer‑reviewed journals and present results at national and international conferences.
Minimum Education and Experience Requirements
Ph.D. in human genetics, bioinformatics, computational biology, or a closely related field.
Demonstrated publication record that evidences research productivity and independent inquiry.
Required Qualifications, Competencies, and Experience
Excellent communication, organizational, and written communication skills.
Strong analytical and problem‑solving abilities with a drive for innovative research.
Willingness and aptitude to work collaboratively in a team‑science environment.
Ability to work independently and manage multiple projects within defined deadlines.
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