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Laboratory Technician - Service Fulfillment

Nuclera Nucleics Ltd, Boston, MA, United States


Nuclera is a venture-backed, founder-driven biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. The company’s mission is to improve human health by making proteins accessible. We are beginning this mission through the launch of our eProtein Discovery™ platform. eProtein Discovery is a breakthrough protein expression, characterization, and purification technology, consisting of a lab-based benchtop instrument, cloud-based software and proprietary cartridges and consumables. The goal is to enable rapid protein access to life science researchers around the world.
The successful candidate will be responsible for amplifying DNA constructs as well as delivering custom projects using our eProtein Discovery Platform in strict accordance with SOPs and work instructions. This position requires the ability to deliver under tight deadlines, attention to detail and strong organizational skills while working independently in a fast-paced environment. The ideal candidate will have a strong background in protein science, molecular biology, or a related discipline, with proven hands-on experience in an industry setting.
About the role

Perform PCR to prepare DNA constructs for cell-free protein expression
Carry out protein purification, quantification, SDS PAGE analysis and gel filtration chromatography or Surface Plasmon Resonance (SPR) analysis
Execute experiments using Nuclera’s eProtein Discovery Platform
Adhere strictly to Work Instructions and Standard Operating Procedures to ensure consistency and quality
Systematically organize, track and manage large numbers of biological samples
Accurately record and document experimental methods, observations and results
Essential

BSc in biochemistry, molecular biology, or a related discipline, with a minimum of 2 years’ industry experience
Proven track record of generating reliable data and delivering results within tight deadlines
Hands‑on experience in molecular biology techniques including PCR, PCR clean‑up and agarose gel electrophoresis
Experience with protein science techniques, including affinity‑based purification, protein quantification, SDS PAGE analysis
Strong organizational skills
Eligible to work in the UK
Desirable

MSc in biochemistry, molecular biology, or related discipline, with a minimum 1 years’ industry experience
Previous experience in a Contract Research Organization (CRO) and/or the biotechnology industry
Familiarity with liquid handling platforms such as Opentron and KingFisher
Experience using automated electrophoresis systems such as the Fragment Analyzer
Understanding of the principles of cell‑free protein synthesis technologies
Prior experience using protein biophysical characterization techniques such as gel filtration chromatography
Prior experience in expressing and purifying antibodies
Prior experience using antibody functional characterization techniques such as Surface Plasmon Resonance (SPR)
What we offer: In addition to competitive salaries, we offer a range of benefits including:

Company bonus scheme of 5%
Life insurance
Private medical insurance and cash plan
25 days' annual leave + Bank Holidays
Enhanced employer's pension contributions
Enhanced maternity and paternity Leave
Investment in professional development and learning
Access to amenities on Vision Park and in Histon
Fresh fruit, tea, coffee, and snacks in the office
Organised team events

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