Director Clinical Pharmacology
ISoP Weekly Digest, San Francisco, CA, United States
Director Clinical Pharmacology
San Francisco Bay Area (Hybrid)
I’m partnering with an innovative and rapidly growing biotech focused on next-generation biologics to appoint a Director of Clinical Pharmacology.
This is a high-impact role sitting at the heart of clinical development, working across a diverse and cutting-edge pipeline including ADCs, bispecifics and multispecific antibodies in oncology, immunology and beyond.
The Opportunity
You will play a key role in shaping clinical strategy through the design and execution of clinical pharmacology studies, influencing decision-making from early development through to late-stage and regulatory submission.
This is a highly visible position with strong cross-functional exposure across clinical, translational, regulatory and biometrics teams.
Key Focus Areas
Lead PK/PD strategy, dose selection and exposure-response analysis
Design and oversee clinical pharmacology studies across Phases 1–
Apply modeling & simulation to inform development decisions
Contribute to global regulatory strategy (IND, NDA, BLA)
Partner closely with clinical development and translational teams
What They’re Looking For
PhD, MD or PharmD with strong clinical pharmacology expertise
Proven experience across early and late-stage development
Deep understanding of biologics (antibodies, complex modalities)
Strong PK/PD and modeling & simulation capabilities
Ability to operate strategically and influence cross-functional teams
Why this role?
Broad and innovative pipeline
Real scope to shape development strategy
High visibility within a growing organisation
Opportunity to step into or operate at Senior Director level
#J-18808-Ljbffr
San Francisco Bay Area (Hybrid)
I’m partnering with an innovative and rapidly growing biotech focused on next-generation biologics to appoint a Director of Clinical Pharmacology.
This is a high-impact role sitting at the heart of clinical development, working across a diverse and cutting-edge pipeline including ADCs, bispecifics and multispecific antibodies in oncology, immunology and beyond.
The Opportunity
You will play a key role in shaping clinical strategy through the design and execution of clinical pharmacology studies, influencing decision-making from early development through to late-stage and regulatory submission.
This is a highly visible position with strong cross-functional exposure across clinical, translational, regulatory and biometrics teams.
Key Focus Areas
Lead PK/PD strategy, dose selection and exposure-response analysis
Design and oversee clinical pharmacology studies across Phases 1–
Apply modeling & simulation to inform development decisions
Contribute to global regulatory strategy (IND, NDA, BLA)
Partner closely with clinical development and translational teams
What They’re Looking For
PhD, MD or PharmD with strong clinical pharmacology expertise
Proven experience across early and late-stage development
Deep understanding of biologics (antibodies, complex modalities)
Strong PK/PD and modeling & simulation capabilities
Ability to operate strategically and influence cross-functional teams
Why this role?
Broad and innovative pipeline
Real scope to shape development strategy
High visibility within a growing organisation
Opportunity to step into or operate at Senior Director level
#J-18808-Ljbffr