Manufacturing Technician III
GlaxoSmithKline, Marietta, PA, United States
Business Introduction
We manufacture and supply reliable, high‑quality medicines and vaccines to meet patients’ needs and drive our performance. Our network of 37 medicines and vaccine manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply. We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.
Position Summary
You will be responsible for leading and executing complex vaccine drug substance manufacturing operations while ensuring compliant, safe, and efficient production. Serves as a technical expert in assigned processes, providing on‑floor leadership, training, problem‑solving support, and continuous improvement. Partners with supervision and cross‑functional teams to ensure consistent execution of manufacturing activities.
Responsibilities
Execute complex drug substance manufacturing operations, including reagent and buffer preparation (weighing, formulation, pH adjustment/titration, filtration, aliquoting) in accordance with approved batch records and SOPs.
Operate and monitor automated process equipment (chromatography, filtration systems, mixers, pumps, meters, scales), ensuring safe, efficient, and compliant execution of manufacturing activities.
Utilize advanced digital systems (electronic batch records, SCADA) to ensure data integrity, monitor process trends, identify deviations, support review by exception manufacturing, and improve overall process outcomes.
Adhere to GMP cleanroom requirements (Grade C/D/CNC gowning and flows) and perform or coordinate environmental monitoring, cleaning, and sanitization activities per approved procedures.
Troubleshoot equipment issues, respond to alarms, recognize early signs of equipment deterioration, and elevate abnormal conditions in a timely manner.
Document equipment status, abnormalities, and actions taken, and contribute to initiatives that improve equipment reliability and extend asset life cycle.
Ensure accurate, contemporaneous GMP documentation; participate in authoring and revising manufacturing and support SOPs; recognize and report deviations and support investigations, root cause analysis, and CAPA development.
Develop and deliver training materials, act as a qualified trainer, support onboarding and qualification of new team members, and provide on‑floor process leadership.
Assist supervisors with daily operations and lead manufacturing activities in the supervisor’s absence as required.
Participate in troubleshooting and continuous improvement initiatives, applying GPS standards (5S, problem solving) to improve safety, quality, delivery, and efficiency.
Basic Qualifications
Minimum bachelor’s degree in biological sciences, chemistry, engineering, or a related technical field. Equivalent combinations of education and experience accepted.
1+ year of manufacturing or production experience.
Leadership experience in a GMP manufacturing environment.
Technical writing experience for GMP documentation (SOPs, MBRs, training materials) with working knowledge of GMP requirements.
Preferred Qualifications
BS or BA in a biological or chemical science degree.
Experience authoring and maintaining technical documentation, including SOPs, work instructions, and training materials in a regulated environment.
Proven experience providing on‑floor leadership and technical guidance within a GMP manufacturing setting.
Ability to safely handle acids, bases, oxidizers, chemicals, and solvents in accordance with procedures and required PPE.
Proficiency in performing basic mathematical calculations and accurately measuring volume and weight.
Strong knowledge of GMP principles and applicable regulatory requirements, with experience applying them in daily operations.
Experience using digital and automated tools (electronic batch records, automation systems, analytics) to support manufacturing execution and improve operational outcomes.
Ability to perform routine physical tasks and lift up to 40 pounds.
Willingness and ability to work first shift on‑site; this role is not hybrid or remote.
Availability to work weekends, holidays, and extra hours when needed.
Effective verbal and written communication for all organizational levels.
Experience with cleanroom operations and equipment such as filtration systems, chromatography, mixers, meters, scales, pumps, and parts washers.
Digital agility, with the ability to quickly learn and effectively use manufacturing and business systems such as SAP, SCADA, MES, and Microsoft Office.
Work Arrangement and Physical Expectations
On‑site in the United States; no hybrid or remote work options. Multiple shift options available; 2nd and 3rd shift eligible for shift differential.
Work in a temperature‑controlled manufacturing area with possible exposure to noise and moving mechanical parts.
Must wear required personal protective equipment.
Role includes standing, walking and physical tasks throughout shift. Overtime may be required.
What We Value
We welcome people from all backgrounds and support an inclusive environment. We place safety and quality first, support learning and career growth, and encourage open collaboration. If you enjoy hands‑on technical work and helping teams improve, we encourage you to apply.
Benefits
To learn more about the comprehensive benefits program for US employees, visit GSK US Benefits Summary.
Equal Opportunity Employer
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important Notice to Employment Businesses/Agencies
GSK does not accept referrals from employment businesses and/or employment agencies for the vacancies posted on this site. All employment businesses/agencies must contact GSK’s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates. Lack of prior written authorization is a condition precedent to any agreement. No fees shall be paid or incurred by GSK for any referrals.
Compliance Information
If you are a US Licensed Healthcare Professional, GSK may be required to capture and report expenses. For more information, visit the Centers for Medicare and Medicaid Services website at https://openpaymentsdata.cms.gov/.
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We manufacture and supply reliable, high‑quality medicines and vaccines to meet patients’ needs and drive our performance. Our network of 37 medicines and vaccine manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply. We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.
Position Summary
You will be responsible for leading and executing complex vaccine drug substance manufacturing operations while ensuring compliant, safe, and efficient production. Serves as a technical expert in assigned processes, providing on‑floor leadership, training, problem‑solving support, and continuous improvement. Partners with supervision and cross‑functional teams to ensure consistent execution of manufacturing activities.
Responsibilities
Execute complex drug substance manufacturing operations, including reagent and buffer preparation (weighing, formulation, pH adjustment/titration, filtration, aliquoting) in accordance with approved batch records and SOPs.
Operate and monitor automated process equipment (chromatography, filtration systems, mixers, pumps, meters, scales), ensuring safe, efficient, and compliant execution of manufacturing activities.
Utilize advanced digital systems (electronic batch records, SCADA) to ensure data integrity, monitor process trends, identify deviations, support review by exception manufacturing, and improve overall process outcomes.
Adhere to GMP cleanroom requirements (Grade C/D/CNC gowning and flows) and perform or coordinate environmental monitoring, cleaning, and sanitization activities per approved procedures.
Troubleshoot equipment issues, respond to alarms, recognize early signs of equipment deterioration, and elevate abnormal conditions in a timely manner.
Document equipment status, abnormalities, and actions taken, and contribute to initiatives that improve equipment reliability and extend asset life cycle.
Ensure accurate, contemporaneous GMP documentation; participate in authoring and revising manufacturing and support SOPs; recognize and report deviations and support investigations, root cause analysis, and CAPA development.
Develop and deliver training materials, act as a qualified trainer, support onboarding and qualification of new team members, and provide on‑floor process leadership.
Assist supervisors with daily operations and lead manufacturing activities in the supervisor’s absence as required.
Participate in troubleshooting and continuous improvement initiatives, applying GPS standards (5S, problem solving) to improve safety, quality, delivery, and efficiency.
Basic Qualifications
Minimum bachelor’s degree in biological sciences, chemistry, engineering, or a related technical field. Equivalent combinations of education and experience accepted.
1+ year of manufacturing or production experience.
Leadership experience in a GMP manufacturing environment.
Technical writing experience for GMP documentation (SOPs, MBRs, training materials) with working knowledge of GMP requirements.
Preferred Qualifications
BS or BA in a biological or chemical science degree.
Experience authoring and maintaining technical documentation, including SOPs, work instructions, and training materials in a regulated environment.
Proven experience providing on‑floor leadership and technical guidance within a GMP manufacturing setting.
Ability to safely handle acids, bases, oxidizers, chemicals, and solvents in accordance with procedures and required PPE.
Proficiency in performing basic mathematical calculations and accurately measuring volume and weight.
Strong knowledge of GMP principles and applicable regulatory requirements, with experience applying them in daily operations.
Experience using digital and automated tools (electronic batch records, automation systems, analytics) to support manufacturing execution and improve operational outcomes.
Ability to perform routine physical tasks and lift up to 40 pounds.
Willingness and ability to work first shift on‑site; this role is not hybrid or remote.
Availability to work weekends, holidays, and extra hours when needed.
Effective verbal and written communication for all organizational levels.
Experience with cleanroom operations and equipment such as filtration systems, chromatography, mixers, meters, scales, pumps, and parts washers.
Digital agility, with the ability to quickly learn and effectively use manufacturing and business systems such as SAP, SCADA, MES, and Microsoft Office.
Work Arrangement and Physical Expectations
On‑site in the United States; no hybrid or remote work options. Multiple shift options available; 2nd and 3rd shift eligible for shift differential.
Work in a temperature‑controlled manufacturing area with possible exposure to noise and moving mechanical parts.
Must wear required personal protective equipment.
Role includes standing, walking and physical tasks throughout shift. Overtime may be required.
What We Value
We welcome people from all backgrounds and support an inclusive environment. We place safety and quality first, support learning and career growth, and encourage open collaboration. If you enjoy hands‑on technical work and helping teams improve, we encourage you to apply.
Benefits
To learn more about the comprehensive benefits program for US employees, visit GSK US Benefits Summary.
Equal Opportunity Employer
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important Notice to Employment Businesses/Agencies
GSK does not accept referrals from employment businesses and/or employment agencies for the vacancies posted on this site. All employment businesses/agencies must contact GSK’s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates. Lack of prior written authorization is a condition precedent to any agreement. No fees shall be paid or incurred by GSK for any referrals.
Compliance Information
If you are a US Licensed Healthcare Professional, GSK may be required to capture and report expenses. For more information, visit the Centers for Medicare and Medicaid Services website at https://openpaymentsdata.cms.gov/.
#J-18808-Ljbffr