Biologist (Genomics)
GAP Solutions Inc, Baltimore, MD, United States
Position Objective
The National Institutes of Health requires contractor support for laboratory and computational analysis of genomic and epigenomic data. The work supports ongoing research involving genotyping, long-range sequencing, and DNA methylation profiling at the National Institute on Aging (NIA) within the National Institutes of Health (NIH).
Duties and Responsibilities
Evaluate read quality, coverage, depth, sample integrity and contamination.
Flag anomalies and provide preliminary interpretation.
Perform DNA extraction from blood, tissue, or cultured cells using established protocols.
Conduct genotyping assays (e.g., SNP arrays, PCR-based methods).
Support long-range sequencing workflows (library prep and sequencing using long-read platforms such as PacBio or Oxford Nanopore).
Perform DNA methylation assays (e.g., bisulfite conversion, array-based or sequencing-based methods).
Execute established QC pipelines for sequencing and genotyping data.
Compile and document QC metrics in standardized formats.
Modify existing scripts and pipelines to support project needs.
Perform data analysis using R (statistical analysis and visualization) and scripting (Python, Bash, or equivalent).
Conduct variant calling and basic annotation and DNA methylation data processing and analysis and data integration across datasets when directed.
Maintain accurate laboratory notebooks and electronic records.
Identify routine technical issues and implement standard troubleshooting steps.
Prepare summary tables, figures and written summaries of methods and results.
Present findings in internal meetings to NIH staff.
Contribute to draft reports, manuscripts, or project updates.
Sample processing logs, DNA extraction records and yields.
Genotyping/Sequencing outputs: raw and processed data files.
QC reports: standardized quality metrics and summaries.
Analysis outputs: variant and methylation results and visualizations.
Scripts and code: documented R/Python/Bash scripts.
Monthly summary of work performed and findings.
Presentation materials: slides or briefings for NIH staff.
Qualifications
Basic Qualifications
Master's degree in Biology or a related field.
At least 2 years of experience.
Proficiency in R and at least one scripting language.
Experience with QC and data visualization.
Familiarity with genomic data formats (FASTQ, BAM, VCF).
Minimum Qualifications
Strong communication skills, both oral and written.
Detail-oriented with strong organizational skills and the ability to prioritize multiple tasks and projects.
Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or other characteristics protected by law.
This position is contingent upon contract award.
GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation, please email recruiting@gapsi.com and reference the requisition number of the position in which you are interested. Emails for any other reason or that do not include a requisition number will not be returned.
#J-18808-Ljbffr
The National Institutes of Health requires contractor support for laboratory and computational analysis of genomic and epigenomic data. The work supports ongoing research involving genotyping, long-range sequencing, and DNA methylation profiling at the National Institute on Aging (NIA) within the National Institutes of Health (NIH).
Duties and Responsibilities
Evaluate read quality, coverage, depth, sample integrity and contamination.
Flag anomalies and provide preliminary interpretation.
Perform DNA extraction from blood, tissue, or cultured cells using established protocols.
Conduct genotyping assays (e.g., SNP arrays, PCR-based methods).
Support long-range sequencing workflows (library prep and sequencing using long-read platforms such as PacBio or Oxford Nanopore).
Perform DNA methylation assays (e.g., bisulfite conversion, array-based or sequencing-based methods).
Execute established QC pipelines for sequencing and genotyping data.
Compile and document QC metrics in standardized formats.
Modify existing scripts and pipelines to support project needs.
Perform data analysis using R (statistical analysis and visualization) and scripting (Python, Bash, or equivalent).
Conduct variant calling and basic annotation and DNA methylation data processing and analysis and data integration across datasets when directed.
Maintain accurate laboratory notebooks and electronic records.
Identify routine technical issues and implement standard troubleshooting steps.
Prepare summary tables, figures and written summaries of methods and results.
Present findings in internal meetings to NIH staff.
Contribute to draft reports, manuscripts, or project updates.
Sample processing logs, DNA extraction records and yields.
Genotyping/Sequencing outputs: raw and processed data files.
QC reports: standardized quality metrics and summaries.
Analysis outputs: variant and methylation results and visualizations.
Scripts and code: documented R/Python/Bash scripts.
Monthly summary of work performed and findings.
Presentation materials: slides or briefings for NIH staff.
Qualifications
Basic Qualifications
Master's degree in Biology or a related field.
At least 2 years of experience.
Proficiency in R and at least one scripting language.
Experience with QC and data visualization.
Familiarity with genomic data formats (FASTQ, BAM, VCF).
Minimum Qualifications
Strong communication skills, both oral and written.
Detail-oriented with strong organizational skills and the ability to prioritize multiple tasks and projects.
Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or other characteristics protected by law.
This position is contingent upon contract award.
GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation, please email recruiting@gapsi.com and reference the requisition number of the position in which you are interested. Emails for any other reason or that do not include a requisition number will not be returned.
#J-18808-Ljbffr