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Scientist – In Vivo Pharmacology

Amgen, South San Francisco, CA, United States


Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. We help pioneer biotech since 1980, focusing on Oncology, Inflammation, General Medicine, and Rare Disease, reaching millions of patients annually. Amgen’s pipeline covers cancer, heart disease, inflammation, rare diseases, and obesity. As a team member, you’ll research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Scientist – In Vivo Pharmacology – Cardiometabolic Disorders
What You Will Do
Let’s do this. Let’s change the world. In this vital role, you will work onsite at Amgen’s South San Francisco campus as part of a collaborative in vivo research team advancing discovery biology and the therapeutic development of the next generation of cardiovascular medicines.

You will contribute to studies that deepen our understanding of cardiovascular disease and help push the boundaries of cardiovascular science in support of innovative drug discovery.

Key Responsibilities

Conduct hands‑on in vivo work in mice, including dosing, handling, health monitoring, and blood collection.

Perform necropsies and collect tissues to support downstream workflows.

Conduct tissue workflow activities, including tissue fixation, trimming, embedding, cry sectioning and/or FFPE sectioning, slide preparation, and sample tracking to ensure high‑quality samples are delivered to downstream groups for analysis.

Maintain tissue and slide quality through proper specimen orientation, labeling, handling, and section QC.

Partner with scientists to execute study plans, communicate progress, and present data and results to study teams.

Maintain accurate experimental records and coordinate sample flow from collection through slide preparation and handoff to downstream groups for analysis.

Participate in dosing and husbandry, including occasional evening or weekend work.

What We Expect Of You
We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a seasoned professional with these qualifications.

Basic Qualifications

Doctorate degree

OR

Master’s degree and 2 years of In Vivo Pharmacology experience

OR

Bachelor’s degree and 4 years of In Vivo Pharmacology experience

Preferred Qualifications

Hands‑on experience on in vivo rodent studies in an academic or industry setting.

Proficiency in mouse techniques such as dosing, blood collection, and health monitoring.

Demonstrated skill in necropsy and in the collection, dissection, and preservation of tissues for histologic and other downstream analyses.

Familiarity with histology workflows, including tissue fixation, processing, embedding, cryosectioning, microtomy, FFPE preparation, slide preparation, and staining methods.

Ability to manage sectioning workflows and prepare high‑quality slides for downstream analysis.

Familiarity with mouse husbandry and vivarium‑based study support.

Cardiovascular in vivo background is a plus.

What you can expect from us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

Benefits

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.

Stock‑based long‑term incentives.

Award‑winning time‑off plans.

Flexible work models where possible.

Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number of applicants or select a candidate for the position.

Sponsorship
Sponsorship for this role is not guaranteed.

Equal Opportunity Employer
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

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