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Postdoctoral Research Associate - The Skellam Lab

University of North Texas System, Granite Heights, WI, United States


Title:

Postdoctoral Research Associate - The Skellam Lab

Employee Classification:

Postdoctoral Research Associate

Campus:

University of North Texas

Division:

UNT-Provost

SubDivision-Department:

UNT-College of Science

Department:

UNT-Biological Sciences-121100

Job Location:

Denton

Salary:

Compensation is competitive and commensurate with the candidate’s qualifications, experience, and discipline, in accordance with university guidelines and available funding.

Full-Time Equivalent (FTE):

1.00

Retirement Eligibility:

ORP Eligible

Position Overview
The Skellam lab at the University of North Texas is seeking a highly motivated and determined Postdoctoral Research Associate with experience in manipulating / engineering eukaryotic cytochrome P450 monooxygenases (P450s) for biotechnological use. This position will investigate the use of P450s as biocatalysts in Nicotinana benthamiana and / or filamentous fungi, testing approaches for enhancing interactions with redox partners, ensure correct anchoring, and designing mutagenesis experiments to diversify substrate scope. The project is highly interdisciplinary and will require knowledge and experience of molecular biology, fungal / plant cell biology, protein modelling, and analytical chemistry techniques. The successful candidate will join a team consisting of postdocs, research assistants, graduate and undergraduate students, in a highly collaborative environment. This project provides opportunities to learn additional techniques such as confocal microscopy, metabolic engineering, and natural product chemistry techniques. Further responsibilities include the day-to-day management of the project, manuscript and proposal writing, presenting original research internally and externally at meetings and conferences, and mentoring students at the undergraduate and graduate level.

Minimum Qualifications

The candidate should have completed their PhD in biochemistry or a related field and have experience and interest in engineering P450 enzymes in eukaryotic hosts

Experience with molecular biology techniques such as gene cloning, plasmid construction, PCR, RT-PCR, Western blots and bioinformatic skills to aid in experimental design

Proficiency with protein structural predictions and protein purification

Ability to work independently

Preferred Qualifications

Experience with agrobacterium / protoplast-mediated transformation

Experience with molecular modeling / docking

A passion for developing biotechnology solutions

Good interpersonal skills and a team-working attitude

Interest in training and mentoring students

Job Duties

Plan & conduct experiments in consultation with Dr. Skellam.

Conduct experiments in accordance with all regulatory and safety policies.

Make scientific observations, keep excellent records of data and interpretations.

Prepare manuscripts for publication based on experimental results to submit to supervisor and publish.

Prepare presentations or presentation materials of results in support of projects.

Work effectively with others when appropriate.

Physical Requirements
Communicating with others to exchange information.

Environmental Hazards
No adverse environmental conditions expected.

Work Schedule
varies based on assignment

Driving University Vehicle
No

Security Sensitive
This is a Security Sensitive Position.

Special Instructions
Applicants must submit a minimum of two professional references as part of their application. If needed, additional references can be added after the application has been submitted.

Benefits
For information regarding our Benefits, click here.

EEO Statement
The University of North Texas System is firmly committed to equal opportunity and does not permit –and takes actions to prevent – discrimination, harassment (including sexual violence, domestic violence, dating violence and stalking), and retaliation on the basis of race, color, religion, national origin, sex, age, disability, genetic information, or veteran status in its application, employment practices, and facilities; nor permits race, color, national origin, religion, age, disability, veteran status, or sex discrimination and harassment in its admissions processes, and educational programs and activities. UNT System Administration promptly investigates complaints of discrimination, harassment, and related retaliation and takes remedial action when appropriate. System Administration also takes actions to prevent retaliation against individuals who oppose any form of harassment or discriminatory practice, file a charge or report, or testify, assist, or participate in a related investigation or proceeding.

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