Research Lab Tech I, Cancer Biology
Brigham and Women's Hospital, Boston, MA, United States
Site: The Brigham and Women's Hospital, Inc.
Job Summary
The research assistant has a key role in identifying therapeutic strategies in pediatric and adult cancers. Previous studies by the lab have led to FDA approval of many new drugs for cancer. The assistant will juxtapose genomic, protein (immunoblotting), and drug‑response studies from cell cultures and mouse models to identify drugs that target essential biologic features in several types of cancer. The research assistant will also help develop novel, high‑throughput technologies that enable efficient evaluation of potential cancer drugs. The candidate will prepare manuscripts for publication in high‑impact science and medicine journals, and may help the PI and others in the lab coordinate national NIH‑funded research programs. The laboratory is primarily interested in the biology and therapeutics of cancer, and an ideal candidate may plan to attend medical or graduate school in 2–3 years.
Principal Duties and Responsibilities
Contribute to genomic and proteomic screens to identify novel therapeutic targets in clinical specimens of human cancer; perform tumor cell cultures and evaluate effects of treating tumor cultures and mouse models with novel therapies.
Carry out genomic (DNA, RNA) analyses by high‑throughput sequencing, protein analyses by immunoblotting, and drug‑response assays.
Record data, summarize and analyze results using basic statistics.
Report on progress of work at weekly laboratory seminars.
Assist in preparing laboratory reagents and chemicals.
Serve as a key team member in preparing high‑impact publications.
Help train new research assistants and postdoctoral fellows in standard methods of molecular biology.
Assist the PI and others in the lab in coordinating national research programs.
Maintain established departmental policies, procedures and objectives, including quality assurance, safety, environmental affairs and infection control.
Qualifications
Bachelor of Science or Bachelor of Arts degree in a biological/physical science is required. Laboratory experience is a plus, and undergraduate coursework or projects that utilize relevant methods will also be considered and may be credited upon hire.
Skills, Abilities and Competencies Required
Ability to carry out procedures in a coordinated, multi‑step manner with appropriate consultation.
Ability to methodically record data and analyze data using basic statistics.
Ability to contribute to manuscript drafts.
Ability to prioritize work.
Remote Type: Onsite
Work Location: 20 Shattuck Street
Scheduled Weekly Hours: 40
Employee Type: Regular
Work Shift: Day (United States of America)
Pay Range: $20.16 – $29.01 hourly
Grade: 5
EEO Statement: 2200 The Brigham and Women’s Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)–282-7642.
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Job Summary
The research assistant has a key role in identifying therapeutic strategies in pediatric and adult cancers. Previous studies by the lab have led to FDA approval of many new drugs for cancer. The assistant will juxtapose genomic, protein (immunoblotting), and drug‑response studies from cell cultures and mouse models to identify drugs that target essential biologic features in several types of cancer. The research assistant will also help develop novel, high‑throughput technologies that enable efficient evaluation of potential cancer drugs. The candidate will prepare manuscripts for publication in high‑impact science and medicine journals, and may help the PI and others in the lab coordinate national NIH‑funded research programs. The laboratory is primarily interested in the biology and therapeutics of cancer, and an ideal candidate may plan to attend medical or graduate school in 2–3 years.
Principal Duties and Responsibilities
Contribute to genomic and proteomic screens to identify novel therapeutic targets in clinical specimens of human cancer; perform tumor cell cultures and evaluate effects of treating tumor cultures and mouse models with novel therapies.
Carry out genomic (DNA, RNA) analyses by high‑throughput sequencing, protein analyses by immunoblotting, and drug‑response assays.
Record data, summarize and analyze results using basic statistics.
Report on progress of work at weekly laboratory seminars.
Assist in preparing laboratory reagents and chemicals.
Serve as a key team member in preparing high‑impact publications.
Help train new research assistants and postdoctoral fellows in standard methods of molecular biology.
Assist the PI and others in the lab in coordinating national research programs.
Maintain established departmental policies, procedures and objectives, including quality assurance, safety, environmental affairs and infection control.
Qualifications
Bachelor of Science or Bachelor of Arts degree in a biological/physical science is required. Laboratory experience is a plus, and undergraduate coursework or projects that utilize relevant methods will also be considered and may be credited upon hire.
Skills, Abilities and Competencies Required
Ability to carry out procedures in a coordinated, multi‑step manner with appropriate consultation.
Ability to methodically record data and analyze data using basic statistics.
Ability to contribute to manuscript drafts.
Ability to prioritize work.
Remote Type: Onsite
Work Location: 20 Shattuck Street
Scheduled Weekly Hours: 40
Employee Type: Regular
Work Shift: Day (United States of America)
Pay Range: $20.16 – $29.01 hourly
Grade: 5
EEO Statement: 2200 The Brigham and Women’s Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)–282-7642.
#J-18808-Ljbffr