Postdoctoral Scientist - AAV Gene Therapy/Extracellular Vesicles/Translational R
Nationwide Children's Hospital, Columbus, OH, United States
Summary
Dr. Nizar Saad’s lab is seeking a postdoctoral scientist to join a translational research program advancing RNA-based and genome-editing therapies for rare genetic diseases. The lab develops RNA-, and CRISPR-based approaches for laminopathies and muscular dystrophies, using viral and non-viral delivery platforms (i.e., AAV and extracellular vesicles (EVs)). The lab also leads EV-based biomarker discovery efforts in muscular dystrophies.
This position will require experience in EV and/or AAV isolation, purification, and characterization, -omics workflows, mouse work, including dosing and tissue collection. Experience in EV and/or AAV engineering is desired. Experience in cardiovascular or skeletal muscle biology is preferred. Additional details at these links: NIH-funded
grant
and Saad Lab
page .
Essential Functions
Conducts research under the guidance of a faculty mentor.
Assists in the training and supervision of technical support staff in performing research essential to carrying out the research program.
Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed.
Assists with the preparation of scientific and technical papers for publication in peer-reviewed journals. Presents findings at local and national research forums.
Collaborates with other ongoing research efforts either at NCH or at The Ohio State University.
Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies.
Education
PhD in relevant scientific field.
Skills
Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues.
Excellent computer skills.
Skills in qualitative and quantitative research methods.
Ability to proactively manage and drive projects.
Experience:
Research experience from PhD program required
Dr. Nizar Saad’s lab is seeking a postdoctoral scientist to join a translational research program advancing RNA-based and genome-editing therapies for rare genetic diseases. The lab develops RNA-, and CRISPR-based approaches for laminopathies and muscular dystrophies, using viral and non-viral delivery platforms (i.e., AAV and extracellular vesicles (EVs)). The lab also leads EV-based biomarker discovery efforts in muscular dystrophies.
This position will require experience in EV and/or AAV isolation, purification, and characterization, -omics workflows, mouse work, including dosing and tissue collection. Experience in EV and/or AAV engineering is desired. Experience in cardiovascular or skeletal muscle biology is preferred. Additional details at these links: NIH-funded
grant
and Saad Lab
page .
Essential Functions
Conducts research under the guidance of a faculty mentor.
Assists in the training and supervision of technical support staff in performing research essential to carrying out the research program.
Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed.
Assists with the preparation of scientific and technical papers for publication in peer-reviewed journals. Presents findings at local and national research forums.
Collaborates with other ongoing research efforts either at NCH or at The Ohio State University.
Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies.
Education
PhD in relevant scientific field.
Skills
Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues.
Excellent computer skills.
Skills in qualitative and quantitative research methods.
Ability to proactively manage and drive projects.
Experience:
Research experience from PhD program required