Specialist, 3DT Biofabrication Scientist (Cambridge, MA)

Job Description
We are seeking a Scientist II who is passionate about developing complex in vitro microphysiological organ‑on‑chip systems (MPS) and bioprinted models for drug discovery and development. The scientist will perform hands‑on experimentation and provide support to advance the team’s biofabrication efforts. The position is based on‑site in Cambridge, MA and supports day‑to‑day laboratory workflows within a collaborative research environment.

Key Responsibilities

Support the biofabrication and maintenance of microphysiological systems and bioprinted models.

Perform routine mammalian cell culture while maintaining a high level of aseptic technique.

Prepare and handle hydrogels/ECM for use in 3‑D culture platforms.

Assist in immunofluorescence staining, imaging, and analysis workflows.

Reconstitute, aliquot, and prepare reagents and media.

Execute multi‑step experimental protocols and workflows.

Document experimental procedures, observations, and results in an electronic lab notebook.

Assist with inventory management, ordering, and general lab maintenance.

Support both general and project‑specific laboratory operations as project needs evolve.

Collaborate across different functional teams and locations.

Required Education
High School Diploma or GED required. Bachelor’s Degree or Master’s Degree preferred. (B.S./B.A. in Bioengineering, Biology, Biomedical Engineering, Cell & Molecular Biology, Immunology, or a related field with minimum of 1 year of relevant experience or Master’s Degree)

Required Experience and Skills

Minimum of 2 years of experience in mammalian cell culture and aseptic technique.

Experience preparing and handling biomaterials or hydrogels for 3‑D culture applications.

Experience working with MPS models, bioprinted platforms, or other 3‑D cell culture technologies.

Familiarity with basic microscopy techniques for assessing cell health and experimental progress.

Strong attention to detail, organizational skills, and accurate documentation practices.

Demonstrated ability to execute experimental protocols and work with collaborators.

Ability to work on‑site, follow established protocols, and meet deadlines.

Enthusiastic, self‑motivated, and eager to learn new workflows.

Preferred Experience and Skills

Experience with stem cell culture or differentiation workflows.

Experience with stem cell‑derived organoid models.

Experience working with MIMETAS organ‑on‑chip or similar high‑throughput platforms.

Experience working in pharmaceutical drug discovery or development.

Data analysis experience using MATLAB, R, and/or Python.

Experience with nucleofection.

US and Puerto Rico Residents Only
Applicants must be U.S. or Puerto Rico residents.

Equal Employment Opportunity
Merck is an Equal Employment Opportunity Employer. We provide equal opportunities for all employees and applicants and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other legally protected characteristic. As a federal contractor, we comply with affirmative action requirements for protected veterans and individuals with disabilities.

Salary
$87,300.00 – $137,400.00

Benefits
We offer a comprehensive benefits package that includes medical, dental, vision, retirement benefits (401(k)), paid holidays, vacation, and other insurance coverage for employees and families.

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