
Scientist- In Vivo (South San Francisco)
Surf Search, South San Francisco, CA, United States
We are looking for a scientist with hands-on experience in animal models to support the development of gene-based therapies for oncology applications. This individual will play a key role in planning and carrying out preclinical studies, contributing to the advancement of internal research programs. The role suits someone with expertise in tumor biology and pharmacology who enjoys working across teams in a fast-paced research environment.
Qualifications of the In Vivo Scientist
PhD in a relevant life sciences field such as immunology, cancer biology, or related discipline
Several years of practical experience working with tumor-bearing animal models in either academic or industry settings
Proven ability to independently design and execute studies and draw meaningful conclusions from data
Experience with in vivo techniques such as surgical procedures and compound administration
Familiarity with cell-based assays, tissue processing, and analytical methods such as flow cytometry; additional histological techniques are beneficial
Experience with cell culture systems
Strong attention to detail and organizational skills
Effective communicator with the ability to work collaboratively across functions
Exposure to regulated research environments is advantageous
Key Responsibilities of the In Vivo Scientist
Plan and carry out in vivo studies in partnership with multidisciplinary teams, ensuring alignment with project timelines and objectives
Identify and implement suitable animal models and experimental approaches to assess therapeutic activity, safety, and biological mechanisms
Conduct laboratory-based animal work, including dosing via multiple routes, tumor model establishment, imaging techniques, and routine monitoring
Handle and process biological samples, including cell isolation and analysis using flow cytometry and immunoassays
Analyze and interpret experimental findings, maintaining clear and thorough documentation
Coordinate with external research organizations and collaborators as needed
Qualifications of the In Vivo Scientist
PhD in a relevant life sciences field such as immunology, cancer biology, or related discipline
Several years of practical experience working with tumor-bearing animal models in either academic or industry settings
Proven ability to independently design and execute studies and draw meaningful conclusions from data
Experience with in vivo techniques such as surgical procedures and compound administration
Familiarity with cell-based assays, tissue processing, and analytical methods such as flow cytometry; additional histological techniques are beneficial
Experience with cell culture systems
Strong attention to detail and organizational skills
Effective communicator with the ability to work collaboratively across functions
Exposure to regulated research environments is advantageous
Key Responsibilities of the In Vivo Scientist
Plan and carry out in vivo studies in partnership with multidisciplinary teams, ensuring alignment with project timelines and objectives
Identify and implement suitable animal models and experimental approaches to assess therapeutic activity, safety, and biological mechanisms
Conduct laboratory-based animal work, including dosing via multiple routes, tumor model establishment, imaging techniques, and routine monitoring
Handle and process biological samples, including cell isolation and analysis using flow cytometry and immunoassays
Analyze and interpret experimental findings, maintaining clear and thorough documentation
Coordinate with external research organizations and collaborators as needed