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Research Technician - Sehgal Lab

Howard Hughes Medical Institute (HHMI), Meadville, PA, United States


Primary Work Address: Clinical Res. Bldg., Room 405, Philadelphia, PA, 19104-6148

About The Lab
The Sehgal Lab, led by Dr. Amita Sehgal at the University of Pennsylvania, focuses on the genetic and molecular mechanisms underlying sleep and circadian rhythms. The lab uses a combination of model organisms, including Drosophila and mouse models, to better understand how biological clocks regulate behavior and physiology.

The team is highly collaborative and provides a strong training environment for early‑career scientists interested in gaining hands‑on research experience.

For more information about the lab, please visit: https://www.med.upenn.edu/sehgallab/

About The Role
The Research Technician I will support ongoing research focused on the genetic and molecular analysis of sleep and circadian rhythms. This role is ideal for a recent graduate seeking 2–3 years of hands‑on research experience prior to pursuing a Master’s, PhD, or MD.

The position offers exposure to a wide range of experimental techniques and the opportunity to contribute meaningfully to active research projects in a dynamic lab environment. It is best suited for early‑career candidates looking to gain research experience before pursuing advanced education.

The ideal start timeline for this position is July 2026.

What You’ll Get

Access to seminars and academic programming at UPenn

Opportunities to contribute to research and publications

Participation in lab retreats and networking opportunities

Exposure to a highly collaborative academic research environment

Comprehensive benefits package

What You’ll Do

Assist with day‑to‑day research activities and support lab members with experiments

Perform Drosophila and/or mouse husbandry, including breeding and genotyping

Conduct behavioral assays and assist with data collection and analysis

Perform molecular biology techniques such as PCR, Western blotting, and other assays

Support tissue culture and sample preparation for histology

Utilize microscopy for imaging and analysis as needed

Assist with general lab operations, including preparing media/reagents and receiving supplies

Collaborate closely with senior research staff on experimental setup and execution

Education & Experience

Bachelor’s degree in life sciences or a related field (required)

0–1 year of research experience (undergraduate research strongly preferred)

Technical Skills

Background in molecular biology and/or cell biology

Experience with PCR, Western blotting, or similar assays

Experience with microscopy preferred

Experience working with animal models (mouse or Drosophila), including breeding/genotyping, preferred

Exposure to behavioral assays is a plus

Core Competencies

Strong interpersonal and collaboration skills

Ability to manage multiple tasks in a fast‑paced lab environment

Highly organized with attention to detail

Goal‑oriented, with interest in pursuing graduate or medical school

Motivated, proactive, and eager to learn new techniques

Physical Requirements
You should be able to remain in a normal seated or standing position for extended periods of time; reach and grasp by extending hand(s) or arm(s); possess dexterity to manipulate objects with fingers, for example using a keyboard; communicate using spoken word; see and hear within normal parameters; and move about the workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids, and presence of carcinogenic substances or other hazardous materials.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note
This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.

Compensation and Benefits
Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more.

Compensation Range: $16.73 (minimum) – $20.94 (midpoint) – $27.21 (maximum)

Pay Type: Hourly

Equal Opportunity Employer
We use E-Verify to confirm the identity and employment eligibility of all new hires.

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