He also answered the Jessica Simpson question in Japanese. Seriously:
Seacrest: I have to ask you—
Mayer: [interrupts] No you don’t.
Seacrest: Yes I do —
Mayer: — but whatever. No you don’t “have to,” say you “want to” ask me. Be a man, be a man!
Seacrest: I want to ask you about Jessica Simpson. I want to ask if the two of you are dating? And, if so, when will we officially see you out together?
Mayer: [Speaks in Japanese, roughly translated: "She is very beautiful and you are the last to know." UPDATED TRANSLATION: "She's a very gorgeous (or well put-together) woman and being together with her is the best."]
Seacrest: I think that’s fantastic. And I’m happy for you.
Mayer: Take it to the room. Find a Japanese person and decode it. Subtitle it. And then you’ll have your answer.
Seacrest: Are you happy?
Mayer: I’m very happy … with what I just did to you.
Seacrest: Yeah, exactly. Thanks, buddy. [Mayer leaves] Good to see you Johnny, take care, have fun! Bye!