Best San Francisco 49ers fantasy performances so far this season
Every season in the NFL produces performances that feel less like a single game and more like statistical outliers — explosive outings where quarterbacks pile up passing yards, running backs break off long scoring runs, and receivers turn routine targets into multi-touchdown afternoons. These are the kinds of games that separate good fantasy weeks from historic ones.
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Stacker compiled a ranking of the best San Francisco 49ers fantasy performances in the 2026 season using data from Stathead. The list includes the highest single-game fantasy scores by quarterbacks, running backs, wide receivers, and tight ends. Players are ranked based on standard fantasy scoring.
Best quarterback fantasy games
#5. Brock Purdy, October 11, 2026
– Stats: 189 Passing Yards, 2 Passing TDs, 1 Interceptions
– Game: SFO vs SEA, 32-29 Win
– Fantasy points: 16.16
#4. Brock Purdy, October 4, 2026
– Stats: 218 Passing Yards, 2 Passing TDs, 0 Interceptions, 29 Rushing Yards
– Game: SFO vs DEN, 24-14 Win
– Fantasy points: 19.62
#3. Brock Purdy, September 10, 2026
– Stats: 205 Passing Yards, 3 Passing TDs, 1 Interceptions, 29 Rushing Yards
– Game: SFO vs LAR, 27-7 Win
– Fantasy points: 21.1
#2. Brock Purdy, September 20, 2026
– Stats: 287 Passing Yards, 2 Passing TDs, 0 Interceptions, 30 Rushing Yards, 1 Rushing TDs
– Game: SFO vs MIA, 35-13 Win
– Fantasy points: 28.48
#1. Brock Purdy, September 27, 2026
– Stats: 297 Passing Yards, 4 Passing TDs, 0 Interceptions, 34 Rushing Yards
– Game: SFO vs ARI, 36-30 Win
– Fantasy points: 31.28
Best running back fantasy games
#5. Christian McCaffrey, September 10, 2026
– Stats: 68 Rushing Yards, 0 Rushing TDs, 20 Receiving Yards
– Game: SFO vs LAR, 27-7 Win
– Fantasy points: 8.8
#4. Christian McCaffrey, October 4, 2026
– Stats: 52 Rushing Yards, 1 Rushing TDs, 18 Receiving Yards
– Game: SFO vs DEN, 24-14 Win
– Fantasy points: 13.0
#3. Christian McCaffrey, October 11, 2026
– Stats: 68 Rushing Yards, 1 Rushing TDs, 15 Receiving Yards
– Game: SFO vs SEA, 32-29 Win
– Fantasy points: 14.3
#2. Christian McCaffrey, September 27, 2026
– Stats: 75 Rushing Yards, 1 Rushing TDs, 41 Receiving Yards
– Game: SFO vs ARI, 36-30 Win
– Fantasy points: 17.6
#1. Christian McCaffrey, September 20, 2026
– Stats: 23 Rushing Yards, 2 Rushing TDs, 43 Receiving Yards
– Game: SFO vs MIA, 35-13 Win
– Fantasy points: 18.6
Best wide receiver fantasy games
#5. Demarcus Robinson, September 10, 2026
– Stats: 50 Receiving Yards, 1 Receiving TDs, 2 Receptions, 3 Targets
– Game: SFO vs LAR, 27-7 Win
– Fantasy points: 11.0
#4. Deebo Samuel, September 10, 2026
– Stats: 48 Receiving Yards, 1 Receiving TDs, 6 Receptions, 7 Targets
– Game: SFO vs LAR, 27-7 Win
– Fantasy points: 12.0
#3. Deebo Samuel, October 4, 2026
– Stats: 26 Receiving Yards, 1 Receiving TDs, 5 Receptions, 6 Targets
– Game: SFO vs DEN, 24-14 Win
– Fantasy points: 13.0
#2. Deebo Samuel, September 27, 2026
– Stats: 80 Receiving Yards, 1 Receiving TDs, 0 Receptions, 0 Targets
– Game: SFO vs ARI, 36-30 Win
– Fantasy points: 15.4
#1. Mike Evans, October 11, 2026
– Stats: 113 Receiving Yards, 1 Receiving TDs, 7 Receptions, 10 Targets
– Game: SFO vs SEA, 32-29 Win
– Fantasy points: 19.3
Best tight end fantasy games
#5. Luke Farrell, September 10, 2026
– Stats: 19 Receiving Yards, 0 Receiving TDs, 2 Receptions, 2 Targets
– Game: SFO vs LAR, 27-7 Win
– Fantasy points: 1.9
#4. George Kittle, October 11, 2026
– Stats: 24 Receiving Yards, 0 Receiving TDs, 5 Receptions, 6 Targets
– Game: SFO vs SEA, 32-29 Win
– Fantasy points: 2.4
#3. George Kittle, October 4, 2026
– Stats: 70 Receiving Yards, 1 Receiving TDs, 4 Receptions, 6 Targets
– Game: SFO vs DEN, 24-14 Win
– Fantasy points: 13.0
#2. George Kittle, September 20, 2026
– Stats: 80 Receiving Yards, 1 Receiving TDs, 4 Receptions, 4 Targets
– Game: SFO vs MIA, 35-13 Win
– Fantasy points: 14.0
#1. George Kittle, September 27, 2026
– Stats: 82 Receiving Yards, 2 Receiving TDs, 6 Receptions, 7 Targets
– Game: SFO vs ARI, 36-30 Win
– Fantasy points: 20.2
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