In this month’s issue of Playboy — don’t ask — “Family Guy” creator and FOX comedy mastermind Seth MacFarlane, had some interesting things to say about Rupert Murdoch, Fox News Channel, and some FNC talent:

MacFarlane: There are things I don’t like about FOX, most notably Fox News, but [Rupert] Murdoch is clearly a shrewd businessman first and a conservative second…He seems to be much more of a critical thinker than the guys he employs at Fox News. If Sean Hannity could think as critically as Rupert, I might like him.

When asked about how his success is helping pay the salaries of Hannity and Bill O’Reilly, McFarlane responded: “I guess if some of it could go toward hiring a dermatologist for O’Reilly and a dietitian for Hannity, I’d feel better about it.” Zing!

As far as appearing on Fox News, MacFarlane went on to say, “I would do it in a second. I love arguing with people I disagree with. Those guys are fundamentally wrong about so much, but they’re also superb debaters.”

Apparently, MacFarlane’s biggest show, “Family Guy,” is about to get a little more political this season. He recently told The Hollywood Reporter that Karl Rove and Rush Limbaugh will be playing themselves in upcoming episodes.

Click continued to see MacFarlane’s ad for Hulu…